Abbott Laboratories : Real-World Data from Abbott's FreeStyle® Libre Show Association Between Higher Frequency of Glucose Monitoring and Improved Glucose Control for People with Diabetes

Empowering Patients with Actionable Information
According to a published report in Patient Preference and Adherence[5] people test with traditional self-monitoring methods (pricking a finger with a lancet to get a blood sample) less than three times per day, which falls short of U.S.[2] and European[3] guidelines that recommend four to eight self-tests per day. People with diabetes cite the biggest obstacle to more frequent monitoring is the pain and hassle of routine fingersticks[5].

But when people with diabetes don't have a clear picture of their glucose levels from regular monitoring, complications such as hypoglycemia can become life-threatening and require hospitalization, which can lead to a significant increase in healthcare costs.

Abbott's FreeStyle Libre system, which was introduced in Europein 2014, removes the need for routine fingersticks[6],[7] - and the pain and hassles that come along with them[8]. In addition, FreeStyle Libre system is factory calibrated-meaning that it does not require a fingerstick test for calibration (a test requiring a blood sample to reset a system's accuracy) unlike other continuous glucose monitoring systems, which require two or more fingersticks per day to remain accurate.

'My experience with FreeStyle Libre through daily clinical practice and research studies has been very positive,' says Ramzi Ajjan, M.D., University of Leeds, U.K.'Patients report that the system helped them gain a better understanding of their glycaemia by enabling multiple daily glucose checks discreetly and conveniently. The system's painless nature of glucose testing are praised by patients with one commenting to me, 'you saved my fingers.' The real-world data further confirms that patients are checking glucose more frequently, up to 16 times per day on average, which is cumbersome to maintain with the conventional fingerstick method. With comprehensive glucose data, patients now have access to more meaningful information key for optimizing their glycaemia control.'

Real-World Usage Supports Randomized Controlled Data of FreeStyle Libre
The new real-world data presented at ATTD further support the conclusions of the randomized controlled clinical studies conducted by Abbott with the FreeStyle Libre system including the IMPACT study[9] published in The Lancet in September 2016.

Key findings of the IMPACT trial included (FreeStyle Libre users versus traditional SMBG):

• Glucose monitoring increased to an average of 15 scans per day
• 38 percent reduction in time spent in hypoglycemia (<70 mg/dl)
• 50 percent reduction in serious hypoglycemia (<55 mg/dl)
• 40 percent reduction in time spent in nocturnal hypoglycemia at night (11 p.m. to 6 a.m.)
• No increase in HbA1c at six months

In 2014, Abbott launched the FreeStyle Libre system in several countries in Europe. Currently, FreeStyle Libre system is available in more than 30 countries around the globe and is being used by more than 250,000 people living with diabetes. In the U.S., the FreeStyle Libre system is currently under review by the U.S. Food and Drug Administration[10].

About the Data
De-identified data was collected over a period of 18 months when FreeStyle Libre readers were connected to the PC-based software with an active internet connection. All information was aggregated. No personal data was utilized or shared.

About Abbott′s FreeStyle Libre System
Abbott′s FreeStyle Libre system consists of a small, round sensor-approximately the size of two stacked U.S. quarters-worn on the back of the upper arm for up to 14 days, which measures glucose every minute in interstitial fluid through a small (5mm long, 0.4mm wide) filament that is inserted just under the skin and held in place with a small adhesive pad. A reader is scanned over the sensor to get a glucose result painlessly[4] in less than one second. Each scan displays a real-time glucose result, a historical trend and the direction the glucose is heading.

The FreeStyle Libre system generates an Ambulatory Glucose Profile (AGP) that provides a visual snapshot of glucose levels, trends and patterns over time.

About Abbott:
At Abbott, we're committed to helping people live their best possible life through the power of health. For more than 125 years, we've brought new products and technologies to the world -- in nutrition, diagnostics, medical devices and branded generic pharmaceuticals -- that create more possibilities for more people at all stages of life. Today, 94,000 of us are working to help people live not just longer, but better, in the more than 150 countries we serve.

Connect with us at www.abbott.com, on Facebook at www.facebook.com/Abbott and on Twitter @FreeStyleDiabet, @AbbottNews and @AbbottGlobal.

SOURCE Abbott