Agilent Technologies Inc. : Agilent Technologies Expands HaloPlex Target Enrichment for Ion Torrent Next-Generation Sequencers
06/04/2012| 01:13pm US/Eastern

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SANTA CLARA, Calif., June 4, 2012
Agilent Technologies Inc. (NYSE: A) today announced the
expansion of the HaloPlex target
enrichment system, which will now be available on Ion
Torrent's Personal Genome Machine, a benchtop sequencing
solution.
The HaloPlex system features a unique paired-end design,
which positions reads at both target ends using a single-end
sequencing run. By taking advantage of the extra coverage
that the paired-end design provides, researchers will be able
to save sequencing costs and time.
"The HaloPlex technology makes it possible for us to
capture specific sets of genes in a single reaction,"
said Peter Ray, head of molecular genetics at The Hospital
for Sick Children in Toronto, Canada. "So far we have
gotten great coverage of the mutations we were looking for.
By combining HaloPlex with Ion Torrent we are able to
generate sequencing data for our targets in a single
day."
HaloPlex continues to break barriers common to other target
enrichment technologies and can now enable larger capture
sizes during desktop sequencing - up to 5Mb or approximately
2,000 genes on a MiSeq personal sequencer. HaloPlex offers
greater efficiency and improved performance and, with the
update released today, it allows researchers to process up to
250,000 amplicons in the same tube.
"HaloPlex is helping to transform target enrichment,
especially for desktop sequencers," said Olle Ericsson,
director of marketing, DNA sequencing at Agilent. "We
are overcoming previous barriers with the fastest, most
flexible and most innovative target enrichment platform on
the market."
The Haloplex system's fast-scaling target enrichment
technology demonstrates Agilent's ongoing commitment to
enabling a better research workflow regardless of the
sequencer platform being used.
HaloPlex is a flexible and customizable product that enables
users to create designs in less than 10 minutes to enrich
thousands of genomic targets, using the no-charge
Web Design Wizard.
Agilent acquired Halo Genomics of Uppsala, Sweden, and the
HaloPlex platform in December, 2011. HaloPlex technology
complements the existing Agilent SureSelect target-enrichment
system.
For more information, visit www.agilent.com/genomics/ngs.
About Agilent Technologies
Agilent Technologies Inc. (NYSE: A) is the world's
premier measurement company and a technology leader in
chemical analysis, life sciences, electronics and
communications. The company's 18,700 employees serve
customers in more than 100 countries. Agilent had net
revenues of $6.6 billion in fiscal 2011.www.agilent.com.
# # #
Contact:
Eric Endicott
+1 408 553 2005
eric_endicott@agilent.com
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