Almirall : and Nuevolution enter into a Strategic Collaboration to Develop RORγt inhibitors for treatment of Dermatology diseases and Psoriatic Arthritis

• Almirall obtains rights to Nuevolution's RORt inhibitor program to identify and develop novel small molecule therapeutics for inflammatory skin diseases as well as Psoriatic Arthritis (PsA)
• Nuevolution will receive an upfront payment of EUR 11.2 million (SEK 109.4 million*), and is eligible to receive development and regulatory milestone payments of up to in total maximum of EUR 172 million (SEK 1.7 billion*) provided successful development, and tiered commercial sales milestones of up to in total maximum of EUR 270 million (SEK 2.6 billion*). Nuevolution would further be entitled to receive tiered royalties on future net sale
• Almirall will be responsible for funding of any further research as well as pre-clinical, clinical, regulatory and commercial activities

As part of the agreement, the parties will also establish a research collaboration for the identification of additional RORgt inhibitors, with an exclusive option for Almirall to use within the dermatological field and with the optional use outside the field of collaboration for Nuevolution.

Almirall will be responsible for funding of any further research as well as pre-clinical, clinical, regulatory and commercial activities. Nuevolution will be responsible for funding of any of its own research.

Nuevolution will receive an upfront payment of EUR 11.2 million (SEK 109.4 million*), and is eligible to receive development and regulatory milestone payments of up to in total maximum of EUR 172 million (SEK 1.7 billion*) provided successful development, and tiered commercial sales milestones of up to in total maximum of EUR 270 million (SEK 2.6 billion*). Nuevolution would further be entitled to receive tiered royalties on future net sales.

'We are extremely excited about entering into this collaboration with Almirall,' said Alex Haahr Gouliaev, CEO of Nuevolution and continued, 'Almirall is a world leading pharmaceutical company in the field of treating dermatological diseases, and through the partnership with Almirall our program has found a strong partner for the continued development and later commercialization. We are looking forward to an excellent working relationship with Almirall.'

Eduardo Sanchiz, CEO of Almirall, commented: 'This agreement with Nuevolution will allow us to develop RORgt inhibitors for the potential treatment of Dermatology diseases and Psoriatic Arthritis, and this program includes novel NCEs with potential to be one of the first entries into a new class of oral non-steroidal anti inflammatories. We are very pleased with this strategic collaboration with Nuevolution, which reinforces our pipeline and brings an additional potential growth driver to Almirall, as we continue to position ourselves as a leading Dermatology player. It also shows our lasting commitment to bringing innovation in from the best sources'.

About payment scheme

The upfront payment is paid to Nuevolution upon signing of the collaboration agreement, subject to standard payment terms, and represent a guaranteed payment. Pre-clinical, clinical and regulatory milestone payments are contingent on successful development, and commercial milestones are contingent on successful achievement of sales milestones. Therefore, none of these payments are guaranteed. Payments from Almirall may be subject to Spanish withholding tax, which may be deductible in Nuevolution's Danish corporate tax.

* Exchange rate 1,00 EUR - 9,7667 SEK

About Nuevolution

Nuevolution AB (publ) is a leading small molecule drug discovery biotech company founded in 2001, headquartered in Copenhagen, Denmark. Nuevolution partners its proprietary discovery platform and programs with pharmaceutical and biotechnology companies to seek future benefit of patients in need of novel medical treatment options. Nuevolution's internal programs are focused on therapeutically important targets within inflammation, oncology and immuno-oncology.

This information is information that Nuevolution AB (publ) is obliged to make public pursuant to the EU Market Abuse Regulation and the Securities Market Act. The information was sent for publication, through the agency of the contact persons set out below, on Monday 12 December, 11:00 (CET).

Nuevolution AB (publ) is listed at Nasdaq First North Premier in Stockholm, Sweden (ticker: NUE.ST). Redeye AB acts as Certified Adviser to Nuevolution AB (publ). More information about Nuevolution can be found on: www.nuevolution.com

Media and Investor Relation's Contact:

Alex Haahr Gouliaev, Chief Executive Officer

Nuevolution AB (publ) Phone: +45 7020 0987

Email: ahg@nuevolution.com

Henrik D. Simonsen, Chief Financial Officer

Nuevolution AB (publ) Phone: +45 7020 0987

Email: hs@nuevolution.com