Reports on Malaria from Bayer CropScience Provide New Insights (Discovery of Rigidified alpha,beta-Unsaturated Imines as New Resistance-breaking Insecticides for Malaria Vector Control)
By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Mosquito-Borne Diseases - Malaria is the subject of a report. According to news reporting originating from Monheim, Germany, by NewsRx correspondents, research stated, "During our continuous search for new resistance-breaking insecticides applicable to malaria vector control, a new class of alpha,beta-unsaturated imines was identified by applying the principle of conformational rigidification as a powerful tool for compound optimisation."
Our news editors obtained a quote from the research from Bayer CropScience, "Herein we describe the successful synthesis of these compounds and their biological test results. Our lead compound 16 from this insecticidal class outperforms market standards, notably for the control of mosquito strains that exhibit either metabolic or target-site resistance to these established insecticides."
According to the news editors, the research concluded: "In our model system for insecticide-treated mosquito nets the compound reveals long-lasting efficacy for up to several months."
For more information on this research see: Discovery of Rigidified alpha,beta-Unsaturated Imines as New Resistance-breaking Insecticides for Malaria Vector Control. Chimia, 2016;70(10):694-697. Chimia can be contacted at: Swiss Chemical Soc, Schwarztorstrasse 9, Ch-3007 Bern, Switzerland (see also Mosquito-Borne Diseases - Malaria).
The news editors report that additional information may be obtained by contacting R. Velten, Bayer CropSci AG, Pest Control Chem, D-40789 Monheim, Germany. Additional authors for this research include N. Bohnke, S. Horstmann, A.W.R. Vermeer, S. Werner and R. Velten.
Keywords for this news article include: Monheim, Germany, Europe, Mosquito-Borne Diseases, Protozoan Infections, Organic Chemicals, Insecticides, Mosquitoes, Malaria, Imines, Bayer CropScience.
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