Biofrontera : to Present at the McGuire Woods 9th Annual Pharmaceutical and Medical Device Conference

Leverkusen, Germany, October 16, 2017 - Biofrontera AG (ISIN: DE0006046113), the specialist for the treatment of sun-induced skin cancer, today announced that it will be featured as a presenting company at the McGuire Woods 9th Annual Pharmaceutical and Medical Device Conference, being held on November 16, 2017 in Chicago, IL. The conference is an interactive event addressing business and regulatory issues impacting the pharmaceutical and medical device industries.

Dr. Hermann Lübbert, Biofrontera's Chief Executive Officer, will provide an update on the Company's commercialization and regulatory progress during the live presentation and will also be available for one-on-one meetings with investors.

In addition to the presentation, Dr. Lübbert has also been invited to speak on the conference's Executive Roundtable focused on recent updates in the life sciences industry.

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Biofrontera AG is a biopharmaceutical company specializing in the development, sale and distribution of dermatological drugs and medical cosmetics. The Leverkusen, Germany-based company, which has approximately 130 employees worldwide, develops and distributes innovative products for the care, protection and treatment of the skin. Biofrontera's combination lead product is topical prescription drug Ameluz® and medical device BF-RhodoLED® for the photodynamic therapy (PDT) treatment of superficial skin cancer and its precursors. Ameluz® has been

marketed in the EU since 2012 and in the U.S. since 2016. The Company also markets the Belixos® dermocosmetics series in the EU, which offers specialized care for damaged or diseased skin.

Biofrontera is the first German, founder-led pharmaceutical company to obtain both EU and U.S. approval for a medical drug it has developed itself. The Biofrontera Group was established in 1997 by current CEO, Prof. Dr. Hermann Lübbert, and is listed on the Frankfurt Stock Exchange (Prime Standard).

www.biofrontera.com

This communication expressly or implicitly contains certain forward-looking statements concerning the business activities of Biofrontera AG. These forward-looking statements reflect the opinion of Biofrontera at the time of this communication and involve certain known and unknown risks. The actual results achieved by Biofrontera may differ significantly from future results or performances which are published in its forward-looking statements. Biofrontera assumes no responsibility to update its forward-looking statements.