Bruker Corporation : Bruker Introduces High Definition (HD) and the revolutionary NMR Thermometer(TM) to NMR with the Most Sensitive, Accurate, High Definition NMR Spectrometer
04/16/2012| 09:08am US/Eastern
Recommend:
MIAMI, Apr 16, 2012 (BUSINESS WIRE) --At the Experimental
Nuclear Magnetic Resonance Conference (ENC) 2012, Bruker
introduces the novel AVANCE III HD NMR spectrometer. Thanks
to its new digital RF synthesizer, further enhanced receiver
electronics, redesigned preamplifiers, extended Digital
Lock(TM) and SmartVT(TM) capabilities, Bruker now has further
enhanced the most sensitive and most accurate, highest
performance NMR spectrometer on the market today, bringing
High Definition (HD) technology to AVANCE NMR users.
The AVANCE III HD spectrometer benefits from a
next-generation RF synthesizer with significantly increased
digital integration, incorporating a lower phase noise local
oscillator (LO) and a high speed DA converter running at 960
MHz. This enables extended digital RF power settings up to
NMR frequencies of 1.2 GHz. Together with the new high
dynamic range and high sensitivity preamplifiers, the AVANCE
III HD demonstrates improved spectral purity, fully exploits
the increased sensitivity of the latest NMR probe technology
and enables sensitivity improvements of up to 30% for the
most demanding applications. These include experiments on
bio-molecular samples in buffers or detergents, metabolic
beverage analysis for food safety and quality, and trace
analysis such as impurity detection in drugs and other
pharmaceutical compounds.
With the new AVANCE III HD preamplifiers and the new GaAs
FET-based broad-band technology, solid-state NMR applications
in particular will directly benefit from up to a 20% increase
in sensitivity on 13C and other X nuclei. A novel impedance
matching technology ensures solids spectra with excellent
symmetry, and the active, fast high power transmit/receive
switch guarantees maximum linearity even at the lowest power
levels. The AVANCE III HD now provides solid-state NMR
researchers with access to fully broad-banded capacities and
easier daily routine operation without the need for manual
interaction. A touch-screen display enables high-definition
tuning and matching of the system and monitoring of the probe
status.
With the revolutionary NMR Thermometer(TM) for the first
time, the measurement of the exact internal sample
temperature by NMR itself is possible. This is achieved fully
automatically through the measurement of the chemical shift
difference between two deuterium resonances, rather than
relying on inaccurate external thermocouples. While one
deuterium signal is used for field stabilization, the
chemical shift difference to the second signal is used
together with the SmartVT(TM) to both measure and maintain a
constant temperature within the sample. Based on the
measurement of the actual sample temperature, the NMR
Thermometer(TM) now offers the possibility of up to 50% times
faster on-line regulation of sample temperature, more
efficient compensation for heating effects caused by RF pulse
sequences, or by sample spinning in MAS experiments. This
results in an immediate improvement in the accuracy and
precision of the acquired signal frequencies by up to a
factor 5, delivering improved accuracy in the assignment of
resonances, especially in solid-state, and 2D/3D/4D protein
and biomolecular NMR applications.
"With our unsurpassed commitment to innovation and to
bringing the latest technology to the field of NMR, the new
AVANCE III HD spectrometer once again offers enabling R&D
innovations and performance breakthroughs from our R&D
centers and key customer collaborations to all NMR
customers," said Dr. Frank Laukien, Bruker's
President and CEO.
About Bruker Corporation
Bruker Corporation is a leading provider of high-performance
scientific instruments and solutions for molecular and
materials research, as well as for industrial and applied
analysis. For more information about Bruker Corporation
(NASDAQ: BRKR), please visit
www.bruker.com
SOURCE: Bruker Corporation
Bruker Corporation
Dr. Thorsten Thiel, +49 (721) 5161 - 6517
Bruker Director of Marketing Communications
thorsten.thiel@bruker.com
distributed by
|
|
Recommend :
