SOUTH SAN FRANCISCO, Calif., Oct. 16, 2017 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (Nasdaq:CTMX), a biopharmaceutical company developing investigational Probody™ therapeutics for the treatment of cancer, today announced that preclinical results will be presented at the 2017 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. The conference will take place October 26-30 in Philadelphia.

Abstract Information:

Title: EGFR-CD3 bispecific Probody therapeutic induces tumor regressions and increases maximum tolerated dose >60 fold in preclinical studies
Session Category:EGFR/Her2
Date:Saturday, October 28
Time:Poster Session A:  12:30 p.m. – 4:00 p.m.
Location:Hall E, Pennsylvania Convention Center
Abstract: A164

The EGFR-CD3 bispecific Probody therapeutic poster will also be included in the Spotlight on Proffered Papers session starting at 10:50 a.m. on Friday, October 27 in the Terrance Ballroom, 400 level.

Title: Optimizing a CD71-targeting Probody drug conjugate (PDC) for activity in multiple solid tumor and lymphoma models and for tolerability in nonhuman primates
Session Category:Therapeutic Agents: Biological
Date:Sunday, October 29
Time:Poster Session B:  12:30 p.m. – 4:00 p.m.
Location:Hall E, Pennsylvania Convention Center
Abstract: B116


Title: A multi-analyte HPLC-MS/MS approach to assessing exposure of a Probody drug conjugate (PDC) in preclinical studies
Session Category:Therapeutic Agents: Biological
Date:Sunday, October 29
Time:Poster Session B:  12:30 p.m. – 4:00 p.m.
Location:Hall E, Pennsylvania Convention Center
Abstract: B103


Title: Nonclinical safety evaluation of two distinct second generation variants of anti-CTLA4 monoclonal antibody, ipilimumab, in monkeys
Session Category:Therapeutic Agents: Biological
Date:Sunday, October 29
Time:Poster Session B:  12:30 p.m. – 4:00 p.m.
Location:Hall E, Pennsylvania Convention Center
Abstract: LB-B33

About CytomX Therapeutics
CytomX Therapeutics is a clinical-stage biopharmaceutical company with a deep and differentiated oncology pipeline of Probody™ therapeutics. Probody therapeutics exploit unique conditions of the tumor microenvironment to more effectively localize antibody binding and activity while limiting activity in healthy tissues. The Company’s pipeline includes proprietary cancer immunotherapies against clinically-validated targets, such as PD-L1 and first-in-class Probody drug conjugates against highly attractive targets, such as CD166 and CD71, which are considered to be inaccessible to conventional antibody drug conjugates due to their presence on healthy tissue. In addition to its wholly owned programs, CytomX has strategic collaborations with AbbVie, Bristol-Myers Squibb Company, Pfizer Inc., MD Anderson Cancer Center and ImmunoGen, Inc.  For more information, visit www.cytomx.com or follow us on Twitter.

Media Contact:
Spectrum
Amir Khan
akhan@spectrumscience.com
212-899-9730

Investor Contact:
Trout Group
Pete Rahmer
prahmer@troutgroup.com
646-378-2973 

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