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Echo Therapeutics, Inc. (NASDAQ: ECTE) shares closed up 14.68 percent on Wednesday with over 3 million shares traded. The stock had one of the biggest percentage advances on the NASDAQ. The company announced earlier this week that it entered into a strategic collaboration agreement with Medical Technologies Innovation Asia, Hong Kong, for a license arrangement and equity investment in Echo. Under the terms of the License, Development and Commercialization Agreement, dated December 9, 2013, between MTIA and Echo, Echo granted MTIA rights to develop, manufacture, market and distribute Echo's Symphony CGM System on an exclusive basis for the Chinese market, including the Peoples' Republic of China, Hong Kong, Macau and Taiwan.

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Axion International Holdings, Inc. (OTCBB: AXIH) shares closed up 12.90 percent on Wednesday with over 430,000 shares traded. The stock was one of the most active stocks in the OTCBB market and had one of the biggest percentage advances. The company announced earlier this month that its subsidiary, AXION Recycled Plastics Incorporated, signed a 3-year contract to provide recycled materials to a major thermoplastics company. This development reinforces the Company's business strategy of its recently purchased assets and related launch as a recycled materials processor and supplier. The contract is renewable in 12-month increments.

Get more information on Axion International Holdings, Inc. and free access to the in-depth equity report at: www.TrendingWallStreet.com/stockquote/AXIH

Growlife, Inc. (OTCBB: PHOT) shares closed up 19.57 percent on Wednesday with nearly 30 million shares traded. The stock had one of the biggest advances in the OTCBB market. The company announced that Marco Hegyi will assume the position of President and join the Board of Directors. GrowLife, Inc. develops, markets and deploys products and services addressing the needs of legal cannabis growing and retail operations, including hydroponic growing equipment and retail support software.

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AMR Corporation (NASDAQ: AAL) shares closed up 4.46 percent on Wednesday with nearly 40 million shares traded. The stock was one of the most actively traded stocks on the NASDAQ and hit a new 52-week high of $27.20 during intra-day trading. The company was fined by the Department of Transportation on Wednesday after its agents allegedly told customers that some of the airline's fees were government-imposed taxes.

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