For immediate release 7.00am: 10 July 2017

HVIVO PLC

("hVIVO" or the "Company")

Directors' Dealings

hVIVO plc (AIM: HVO), a specialty biopharma company with discovery and clinical testing capabilities, announces that application has been made to AIM for the admission of 21,363 new ordinary shares of 5.0p each in the Company (the "New Ordinary Shares").

The New Ordinary Shares have been allotted pursuant to the purchase by Jaime Ellertson (Non- Executive Chairman) and Jim Winschel (Non-Executive Director) of new ordinary shares, under the terms of their letters of appointment as set out in the Company's announcement of 4 November 2014 which stated that Mr Ellertson and Mr Winschel had entered into binding commitments to purchase

$20,000 and £4,000 of hVIVO plc new ordinary shares respectively per quarter. On 7 June 2017, Jaime Ellertson volunteered to reduce his Director's fee by 10% to $180k pa, and his quarterly purchase of shares by 10% to $18,000, with effect from 1 June '17.

The New Ordinary Shares represent their investments for the quarter ended 30 June 2017. On 7 July 2017, Mr Ellertson invested in an additional 16,888 ordinary shares and Mr Winschel invested in an additional 4,475 ordinary shares, at a price of 89.4 pence per share.

Following admission of the New Ordinary Shares to trading on AIM, the total number of ordinary shares with voting rights in issue will be 78,150,671 and this figure may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the Financial Conduct Authority's Disclosure and Transparency Rules.

Admission of the New Ordinary Shares ("Admission"), which will rank pari passu in all respects with the Company's existing shares in issue, is expected to occur on 13 July 2017. Following Admission, Mr Ellertson and Mr Winschel will be interested in a total of 94,550 and 44,790 ordinary shares of 5.0p in the Company respectively, each representing less than 0.1% of the Company's issued share capital.

The notification below, made in accordance with the requirements of the EU Market Abuse Regulation, provides further detail:

Notification and public disclosure of transactions by persons discharging managerial responsibilities and persons closely associated with them

1

Details of the persons discharging managerial responsibilities/persons closely associated

a)

Name

Jaime Ellertson and Jim Winschel

2

Reason for the notification

a)

Position/ status

Non-Executive Chairman and Non-Executive Director

b)

Initial notification/ Amendment

Initial Notification

Director

Price (p)

Volume

Jaime Ellertson

89.4

16,888

Jim Winschel

89.4

4,475

3

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

hVIVO plc

b)

Legal Entity Identifier

N/A

4

Details of the transaction(s): section to be repeated for (i) each type of instrument;

(ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a)

Description of the financial instrument, type of instrument

Identification code

Ordinary shares of 5 pence each

GB00B6ZM0X53

b)

Nature of the transaction

Acquisition of ordinary shares

c)

Currency

GBP

d)

Price(s) and volume(s)

e)

Aggregated

21,363

information

- Aggregated volume

- Price

89.4p

- Aggregated

£19,098.52

total

f)

Date of the transaction

7 July 2017

g)

Place of the transaction

London Stock Exchange, AIM

For further information please contact:

hVIVO plc

+44 207 756 1300

Kym Denny (Chief Executive Officer)

Graham Yeatman (Chief Financial & Business Officer)

Media Enquiries

+1 919 710 9658

Susan Flood (Head of Marketing)

Numis Securities Limited

+44 207 260 1000

Michael Meade / Freddie Barnfield (Nominated Adviser)

James Black / Michael Burke (Corporate Broking)

FTI Consulting

Simon Conway / Victoria Foster Mitchell (UK)

+44 203 727 1000

John Capodanno / Evan Smith (US)

+1 212 850 5705

Notes to Editors:

hVIVO plc ("hVIVO"), a specialty biopharma company with discovery and clinical testing capabilities, is pioneering a human-based analytical platform to accelerate drug discovery and development in respiratory and infectious diseases. Leveraging human disease models in flu, RSV and asthma exacerbation, the hVIVO platform captures disease in motion, illuminating the entire disease life cycle from healthy to sick and back to health. Based in the UK, market leader hVIVO has conducted more than 45 clinical studies, inoculated over 2000 volunteers and has three first-in-class therapies currently in development with a growing pre-clinical pipeline.

hVIVO plc published this content on 10 July 2017 and is solely responsible for the information contained herein.
Distributed by Public, unedited and unaltered, on 10 July 2017 06:14:11 UTC.

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