Company Karyopharm Therapeutics Inc.

Equities

KPTI

US48576U1060

Biotechnology & Medical Research

Real-time Estimate Cboe BZX 10:59:37 2024-04-16 am EDT 5-day change 1st Jan Change
1.145 USD -0.87% Intraday chart for Karyopharm Therapeutics Inc. -14.93% +31.79%

Business Summary

Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. It is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including multiple myeloma, endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, oral SINE compound that, like selinexor, selectively blocks the nuclear export protein XPO1.

Number of employees: 325

Sales per Business

USD in Million2022Weight2023Weight Delta
Drugs
100.0 %
157 100.0 % 146 100.0 % -7.03%

Sales per region

USD in Million2022Weight2023Weight Delta
United States
100.0 %
157 100.0 % 146 100.0 % -7.03%

Managers

Managers TitleAgeSince
Chief Executive Officer 56 20-02-25
Director of Finance/CFO 49 19-02-24
Chief Tech/Sci/R&D Officer - 23-03-31
Compliance Officer - 21-04-30
Chief Tech/Sci/R&D Officer 46 22-03-31
Investor Relations Contact - 22-03-13
Human Resources Officer - 22-08-31
Corporate Officer/Principal 51 22-01-31
Corporate Officer/Principal 41 21-06-07
General Counsel 47 20-12-14

Members of the board

Members of the board TitleAgeSince
Director/Board Member 76 13-10-02
Director/Board Member 60 12-12-31
Director/Board Member 59 13-03-31
Director/Board Member 51 20-11-24
Director/Board Member 63 10-09-30
Chief Executive Officer 56 20-02-25
Director/Board Member 54 20-08-27
Director/Board Member 47 23-08-30

Share class

VoteQuantityFree-FloatCompany-owned sharesTotal Float
Stock A 1 116,465,736 108,093,698 ( 92.81 %) 0 92.81 %

Shareholders

NameEquities%Valuation
BlackRock Advisors LLC
8.219 %
9,457,310 8.219 % 14 M $
Vanguard Fiduciary Trust Co.
7.570 %
8,710,158 7.570 % 13 M $
Avidity Partners Management LP
7.212 %
8,298,570 7.212 % 13 M $
Palo Alto Investors LP
4.434 %
5,102,193 4.434 % 8 M $
Chione Ltd.
3.824 %
4,400,000 3.824 % 7 M $
Citadel Advisors LLC (13f Subfiler)
2.695 %
3,101,399 2.695 % 5 M $
Geode Capital Management LLC
2.070 %
2,382,428 2.070 % 4 M $
GSA Capital Partners LLP
2.032 %
2,337,985 2.032 % 4 M $
2,053,773 1.785 % 3 M $
Renaissance Technologies LLC
1.707 %
1,964,377 1.707 % 3 M $

Company contact information

Karyopharm Therapeutics, Inc.

85 Wells Avenue Suite 210, 2nd floor

02459-3298, Newton

+617 658 0600

http://www.karyopharm.com
address Karyopharm Therapeutics Inc.(KPTI)
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