Mettler Toledo : Press Release: New PAT Technique Developed By METTLER TOLEDO Indicates How Particle Size, Shape and Concentration Change in Real Time
September 29, 2015 at 07:35 am EDT
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Unlike turbidity measurements which lack sensitivity and can be difficult to interpret, RBI is an image-based measurement that utilizes real-time microscopy to accurately determine particle system reflectivity in-process. RBI is used to study changes in particle size, shape and concentration. Automatically combined with high resolution real-time microscopy images, RBI provides a simple, yet informative, process measurement that can be used to understand, optimize and control complex particle systems.
RBI is available to users of METTLER TOLEDO ParticleView 19 with PVM technology. Combined with real-time microscopy, RBI is an innovation in real-time measurement that combines simplicity with information-rich understanding to provide an easy-to-use technique supporting the development of quality processes in less time at lower costs.
Common RBI applications include solubility and metastable zone width determination (MZWD) for crystallization development; comparing crystallization rate under different process conditions; identifying the endpoint and equilibrium state for particle processes; characterizing process events such as secondary nucleation, droplet coalescence or particle breakage.
Mettler-Toledo International, Inc. specializes in the design, manufacturing and marketing of precision instruments. Net sales break down by sector of activity as follows:
- research and development in laboratories (55.6%): weighing solutions (analytical balances, precision balances, microbalances, mass comparators, etc.), pipetting systems, analytical instruments (thermal analysis instruments, titrators, pH meters, densimeters, refractometers and spectrophotometers), automated reactors, etc. ;
- industries (39.3%): industrial scales, analysis systems, industrial inspection and control systems. The group also offers software solutions for weighing, measuring and identification, as well as solutions to monitor and control production processes;
- distribution of food products (6.1%): weighing solutions (weight / price scales, counter balances, cash balances, etc.), packaging, pricing, packaging and labeling.
Net sales by source of revenue break down between product sales (76.7%) and services (23.3%).
At the end of 2023, the group had 30 production sites worldwide.
Net sales are distributed geographically as follows: the United States (35.5%), the Americas (5.9%), Germany (5.8%), France (3.7%), Switzerland (2.4%), the United Kingdom (2.1%), Europe (12.8%), China (18.7%) and other (13.1%).
METTLER-TOLEDO INTERNATIONAL, INC. 
