NEW YORK, January 31, 2017 /PRNewswire/ --

In today's pre-market research, Stock-Callers.com takes a closer look at some Drug Manufacturers equities to see how they have fared at the close. Lined up for review today are: Depomed Inc. (NASDAQ: DEPO), United Therapeutics Corp. (NASDAQ: UTHR), DURECT Corp. (NASDAQ: DRRX), and Orexigen Therapeutics Inc. (NASDAQ: OREX). These companies are part of the Healthcare sector which was moderately lower late Monday, January 30th, 2017, with the NYSE Health Care Index dropping about 0.5%, while shares of health care companies in the S&P 500 were down almost 0.6% as a group. Learn more about these stocks by downloading their comprehensive and free reports at:

http://stock-callers.com/registration

Depomed

Shares in Newark, California headquartered Depomed Inc. saw a drop of 1.22%, ending Monday's trading session at $17.74. The stock recorded a trading volume of 644,118 shares. The Company's shares are trading 7.09% below their 50-day moving average. Moreover, shares of Depomed, which engages in the development, sale, and licensing of products for pain and other central nervous system conditions in the US, has a Relative Strength Index (RSI) of 40.92. DEPO complete research report is just a click away and free at:

http://stock-callers.com/registration/?symbol=DEPO United Therapeutics

Silver Spring, Maryland headquartered United Therapeutics Corp.'s stock declined 1.70%, closing the day at $159.67 with a total trading volume of 520,989 shares. The Company's shares have advanced 11.68% in the last one month, 37.24% in the previous three months, and 11.32% on an YTD basis. The stock is trading 12.96% above its 50-day moving average and 29.94% above its 200-day moving average. Additionally, shares of United Therapeutics, which develops and commercializes products to address the unmet medical needs of patients with chronic and life-threatening diseases worldwide, have an RSI of 66.31.

On January 19th, 2017, research firm Standpoint Research downgraded the Company's stock rating from 'Buy' to 'Hold'. The complimentary report on UTHR can be downloaded at: http://stock-callers.com/registration/?symbol=UTHR DURECT

On Monday, shares in Cupertino, California headquartered DURECT Corp. recorded a trading volume of 1.32 million shares, which was higher than their three months average volume of 544,970 shares. The stock ended the day 9.32% lower at $1.07. The Company's shares are trading below their 50-day moving average by 17.44%. Furthermore, shares of DURECT, which researches and develops therapies based on its epigenomic regulator program and proprietary drug delivery platforms, has an RSI of 29.55.

On January 30th, 2017, DURECT provided an update on the DUR-928 development program. The Company's first patient trial utilizing DUR-928 was an open-label, single-ascending-dose safety and pharmacokinetic (PK) Phase-1b trial in liver function impaired (NASH) patients and matched control subjects. This study was conducted in Australia in successive cohorts evaluating single-dose levels of orally administered DUR-928. DURECT stated that an abstract for this study has been accepted and data from the study will be presented at the International Liver Congress(TM) 2017 organized by the European Association for the Study of the Liver in Amsterdam, April 19th-23rd, 2017. Sign up for your complimentary research report on DRRX at:

http://stock-callers.com/registration/?symbol=DRRX Orexigen Therapeutics

La Jolla, California headquartered Orexigen Therapeutics Inc.'s stock dropped 1.20%, finishing yesterday's session at $3.30 with a total trading volume of 261,794 shares. The Company's shares have advanced 92.98% in the last one month, 10.74% in the previous three months, and 89.66% since the start of this year. The stock is trading above its 50-day moving average by 34.73%. Additionally, shares of Orexigen Therapeutics, which focuses on the development of pharmaceutical products, have an RSI of 59.19.

On January 25th, 2017, Orexigen Therapeutics announced that Laboratorios Farmace uticos Rovi, S.A. has launched Mysimba in Spain. Mysimba is approved by the European Medicines Agency for the management of weight in adult patients (greater than or equal to18 years) with an initial Body Mass Index (BMI) of greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 to < 30 kg/m2 in the presence of one or more weight-related co-morbidities. ROVI will market Mysimba as part of their diversified pharmaceutical portfolio under the terms of Orexigen Therapeutics' distributorship agreement signed in August 2016. Following a successful partnering process in 2016, Orexigen currently has commercialization arrangements with five different partners covering 38 countries. Get free access to your research report on OREX at:

http://stock-callers.com/registration/?symbol=OREX

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