SHIRE PLC
Notification of major interests in shares
June 18, 2015 - Shire plc (LSE: SHP, NASDAQ: SHPG)
1. Identity of the issuer or the underlying issuer of Shire plc
existing shares to which voting rights are attached:
2. Reason for the notification State
Yes/No
An acquisition or disposal of voting rights Yes
An acquisition or disposal of qualifying financial
instruments which may result in the acquisition of shares No
already issued to which voting rights are attached
An acquisition or disposal of instruments with similar
economic effect to qualifying financial instruments No
An event changing the breakdown of voting rights No
Other (please specify): No
3. Full name of person(s) subject to the notification FMR LLC
obligation:
4. Full name of shareholder(s) (if different from 3.): See Section 9
5. Date of the transaction (and date on which the June 17, 2015
threshold is crossed or reached if different):
6. Date on which issuer notified: June 18, 2015
7. Threshold(s) that is/are crossed or reached: 5%
8. Notified details:
A: Voting rights attached to shares
Situation previous to Resulting situation after the triggering
Class/type of the triggering transaction
shares transaction
if possible
using the ISIN Number Number Number Number of voting % of voting
CODE of of of rights rights
Shares Voting shares
Rights
Indirect Direct Indirect Direct Indirect
29,674,746 29,674,746 29,412,481 29,412,481 4.96
JE00B2QKY057
B: Qualifying Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting % of voting
financial date Conversion rights that may be rights
instrument Period/ Date acquired if the
instrument
is exercised/converted
C: Financial Instruments with similar economic effect to Qualifying Financial
Instruments
Resulting situation after the triggering transaction
Type of Exercise Expiration Exercise/ Number of voting % of voting
financial price date Conversion rights rights
instrument period instrument
refers to
Nominal Delta
Total (A+B+C)
Number of voting rights % of voting rights
29,412,481 4.96
9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:
Custodian Day to Day IM Total
CROSBY ADVS LLC-CROSBY ADVISORS LLC 25,723
BANK OF NEW YORK MELLON PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 347,644
BROWN BROS HARRIMN LTD LUX FMRC-FMR CO., INC 3,900
(C)
BROWN BROTHERS HARRIMAN AND FMRC-FMR CO., INC 7,203,490
CO
FMRIMUK-FMR INVESTMENT MANAGEMENT (UK) 57,900
LIMITED
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 28,719
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 721,869
COMPANY
CIBC MELLON TRUST (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 22,525
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 17,700
COMPANY
CITIBANK NA, HONG KONG BR PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 27,377
(S)
DEUTSCHE BANK ALEX BROWN (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 6,000
JP MORGAN, BOURNEMOUTH (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 16,574
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 30,831
COMPANY
JPMORGAN CHASE BANK FMRC-FMR CO., INC 8,176,441
FMRIMUK-FMR INVESTMENT MANAGEMENT (UK) 482,300
LIMITED
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 41,933
COMPANY
MELLON BANK NA (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 77,068
MORGAN STANLEY AND CO LLC PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 2,100
NATIONAL BANK TRUST (C) PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 25,225
COMPANY
NATIONAL FINANCIAL SERVICES SAI-STRATEGIC ADVISERS, INC. 1,346
(C)
NORTHERN TRUST CO (C) FMRC-FMR CO., INC 2,724,688
FMRIMUK-FMR INVESTMENT MANAGEMENT (UK) 1,669,700
LIMITED
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 110,800
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 44,001
COMPANY
STATE STR BK AND TR CO LNDN PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 34,898
(C
STATE STREET BANK AND TR CO FMRC-FMR CO., INC 6,247,251
FMRIMUK-FMR INVESTMENT MANAGEMENT (UK) 449,700
LIMITED
PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 430,756
PYRAMIS GLOBAL-PYRAMIS GLOBAL ADVISORS TRUST 351,212
COMPANY
US BANK NA (C) PGALLC-PYRAMIS GLOBAL ADVISORS, LLC 32,810
Grand Total 29,412,481
Proxy Voting:
FMR LLC
10. Name of the proxy holder:
11. Number of voting rights proxy holder will cease to 262,265
hold:
12. Date on which proxy holder will cease to hold voting June 17, 2015
rights:
13. Additional information: None
14. Contact name: Sally-Ann Hatton
15. Contact telephone number:
fil-regreporting@fil.com, 01737 837148
For further information please contact:
Investor Relations
Sarah Elton-Farr seltonfarr@shire.com +44 1256 894157
NOTES TO EDITORS
Shire enables people with life-altering conditions to lead better lives.
Our strategy is to focus on developing and marketing innovative specialty
medicines to meet significant unmet patient needs.
We focus on providing treatments in Rare Diseases, Neuroscience,
Gastrointestinal and Internal Medicine and we are developing treatments for
symptomatic conditions treated by specialist physicians in other targeted
therapeutic areas, such as Ophthalmics.
http://www.shire.com/SHIRE : s) in Company
June 18, 2015 at 11:40 am EDT
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