FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE

Rule 8.3 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Identity of the person whose positions/dealings are being disclosed:

D. E. Shaw & Co., L.P.

(b) Owner or controller of interests and short positions disclosed, if different from 1(a):

The naming of nominee or vehicle companies is insufficient


(c) Name of offeror/offeree in relation to whose relevant securities this form relates:

Use a separate form for each offeror/offeree

Shire Plc

(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree:


(e) Date position held/dealing undertaken:

July 29, 2014

(f) Has the discloser previously disclosed, or are they today disclosing, under the Code in respect of any other party to this offer?

Yes: AbbVie Inc

2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:

5p ordinary and ADS


Interests

Short positions

Number

%

Number

%

(1) Relevant securities owned and/or controlled:

477,444

0.08%

6,000

0.00%

(2) Derivatives (other than options):

6,266,446

1.06%



(3) Options and agreements to purchase/sell:



390,000

0.07%

TOTAL:

6,743,890

1.14%

396,000

0.07%

All interests and all short positions should be disclosed.

Details of any open derivative or option positions, or agreements to purchase or sell relevant securities, should be given on a Supplemental Form 8 (Open Positions).

(b) Rights to subscribe for new securities (including directors' and other executive options)

Class of relevant security in relation to which subscription right exists:


Details, including nature of the rights concerned and relevant percentages:


If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE

(a) Purchases and sales

Class of relevant security

Purchase/sale

Number of securities

Price per unit

ADS

Purchase

7,900

USD 250.794

ADS

Purchase

6,806

USD 250.908

ADS

Purchase

200

USD 251.100

ADS

Purchase

200

USD 250.400

(b) Derivatives transactions (other than options)

Class of relevant security

Product description

e.g. CFD

Nature of dealing

e.g. opening/closing a long/short position, increasing/reducing a long/short position

Number of reference securities

Price per unit

5p ordinary

Swap

Increasing a long position

974

GBP 49.252

5p ordinary

Swap

Reducing a long position

971

GBP 49.311

5p ordinary

Swap

Increasing a long position

12,611

GBP 49.221

5p ordinary

Swap

Reducing a long position

8,530

GBP 49.354

5p ordinary

Swap

Increasing a long position

25,000

GBP 49.195

5p ordinary

Swap

Increasing a long position

25,000

GBP 49.345

5p ordinary

Swap

Increasing a long position

25,000

GBP 49.295

5p ordinary

Swap

Increasing a long position

25,000

GBP 49.340

5p ordinary

Swap

Increasing a long position

50,000

GBP 49.210

5p ordinary

Swap

Increasing a long position

58,088

GBP 49.254

5p ordinary

Swap

Increasing a long position

114,035

GBP 49.375

5p ordinary

Swap

Increasing a long position

2

GBP 49.310

5p ordinary

Swap

Increasing a long position

25,000

GBP 49.220

5p ordinary

Swap

Increasing a long position

41,912

GBP 49.380

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Class of relevant security

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Type

e.g. American, European etc.

Expiry date

Option money paid/ received per unit









(ii) Exercising

Class of relevant security

Product description

e.g. call option

Number of securities

Exercise price per unit




(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable)




The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

If there are no such agreements, arrangements or understandings, state "none"

None

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the person making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

None

(c) Attachments

Is a Supplemental Form 8 (Open Positions) attached?

Yes

Date of disclosure:

July 30, 2014

Contact name:

Anastasia Filipenko (Compliance Department)

Telephone number:

+44 (0) 20 7409 4300

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel atmonitoring@disclosure.org.uk. The Panel's Market Surveillance Unit is available for consultation in relation to the Code's dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website atwww.thetakeoverpanel.org.uk.

DETAILS OF OPEN OPTION AND DERIVATIVE POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the "Code")

1. KEY INFORMATION

Identity of person whose open positions are being disclosed:

D. E. Shaw & Co., L.P.

Name of offeror/offeree in relation to whose relevant securities the disclosure relates:

Shire Plc

2. OPTIONS AND DERIVATIVES

Class of relevant security

Product description e.g. call option

Written or purchased

Number of securities to which option or derivative relates

Exercise price per unit

Type

e.g. American, European etc.

Expiry date

5p ordinary

Listed Call Option

Written

100,000

36

American

20140919

ADS

Listed Put Option

Purchased

10,000

160

American

20141017

ADS

Listed Put Option

Purchased

10,000

170

American

20141017

ADS

Listed Put Option

Purchased

10,000

175

American

20141017

5p ordinary

Swap in respect of Put Option

Purchased

100,000

28

American

20141219

5p ordinary

Swap in respect of Put Option

Purchased

100,000

30

American

20150320

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

None.

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to contracts for differences ("CFDs") or spread bets.

The currency of all prices and other monetary amounts should be stated.

The Panel's Market Surveillance Unit is available for consultation in relation to the Code's dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website atwww.thetakeoverpanel.org.uk.


This information is provided by RNS
The company news service from the London Stock Exchange
ENDRETBSGDRSDXBGSG
distributed by