Morgan Stanley & Co. LLC



AMENDMENT (Section 2 (a))

FORM 8.5 (EPT/RI)

PUBLIC DEALING DISCLOSURE BY AN EXEMPT PRINCIPAL TRADER WITH RECOGNISED INTERMEDIARY STATUS DEALING IN A CLIENT-SERVING CAPACITY

Rule 8.5 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Name of exempt principal trader:

Morgan Stanley & Co. LLC

(b) Name of offeror/offeree in relation to whose relevant securities this form relates:

Use a separate form for each offeror/offeree

ABBVIE INC

(c) Name of the party to the offer with which exempt principal trader is connected:

SHIRE PLC

(d) Date dealing undertaken:

21 AUGUST 2014

(e) Has the EPT previously disclosed, or is it today disclosing, under the Code in respect of any other party to this offer?

YES

2. DEALINGS BY THE EXEMPT PRINCIPAL TRADER

(a) Purchases and sales

Class of relevant security

Purchases/sales

Total number of securities

Highest price per unit paid/received

Lowest price per unit paid/received

COMMON SHARES OF USD 0.01 PAR VALUE

PURCHASES

11,200

33.1998 GBP

33.1998 GBP

COMMON SHARES OF USD 0.01 PAR VALUE

PURCHASES

2,111,100

55.1100 USD

54.6600 USD

COMMON SHARES OF USD 0.01 PAR VALUE

SALES

2,030,046

55.1100 USD

54.6600 USD

(b) Derivatives transactions (other than options)

Class of relevant security

Product description

e.g. CFD

Nature of dealing

e.g. opening/closing a long/short position, increasing/reducing a long/short position

Number of reference securities

Price per unit

N/A

N/A

N/A

N/A

N/A

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Class of relevant security

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Type e.g. American, European etc.

Expiry date

Option money paid/ received per unit

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

100

57.5000

A

20/09/2014

0.2000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

400

62.5000

A

17/01/2015

0.5600 USD

COMMON SHARES OF USD 0.01 PAR VALUE

PUT

PURCHASE

1,100

50.0000

A

22/11/2014

0.7000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

700

55.0000

A

20/09/2014

1.0000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

400

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

1,000

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

1,600

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

1,000

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

9,400

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

600

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

1,300

55.0000

A

20/09/2014

1.0500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

100

55.0000

A

20/09/2014

1.0700 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

4,100

55.0000

A

20/09/2014

1.0700 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

200

60.0000

A

17/01/2015

1.0700 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

100

60.0000

A

17/01/2015

1.0800 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

1,000

55.0000

A

20/09/2014

1.1000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

PUT

PURCHASE

5,900

55.0000

A

20/09/2014

1.1000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

PUT

PURCHASE

1,100

55.0000

A

20/09/2014

1.1000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

PUT

PURCHASE

1,300

55.0000

A

20/09/2014

1.1000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

PUT

PURCHASE

1,200

55.0000

A

20/09/2014

1.1000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

100

57.5000

A

22/11/2014

1.1300 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

200

70.0000

A

15/01/2016

1.5000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

200

55.0000

A

22/11/2014

2.1200 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

400

55.0000

A

20/02/2015

3.2000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

400

55.0000

A

20/02/2015

3.2000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

PURCHASE

200

55.0000

A

20/02/2015

3.2900 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

400

65.0000

A

20/02/2015

0.6000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

500

65.0000

A

20/02/2015

0.6000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

100

65.0000

A

20/02/2015

0.6000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

2,500

55.0000

A

20/09/2014

1.2000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

2,600

60.0000

A

20/02/2015

1.5500 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

400

55.0000

A

22/11/2014

2.2000 USD

COMMON SHARES OF USD 0.01 PAR VALUE

CALL

SALE

300

50.0000

A

15/01/2016

8.6900 USD

(ii) Exercising

Class of relevant security

Product description e.g. call option

Number of securities

Exercise price per unit

N/A

N/A

N/A

N/A

(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing e.g. subscription, conversion

Details

Price per unit (if applicable)

N/A

N/A

N/A

N/A

The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(b), copy table 2(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

3. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the exempt principal trader making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

If there are no such agreements, arrangements or understandings, state "none"

None

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the exempt principal trader making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

None

Date of disclosure:

26 AUGUST 2014

Contact name:

Darren Wickert

Telephone number:

+44 (0)20 7425 6578

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel atmonitoring@disclosure.org.uk. The Panel's Market Surveillance Unit is available for consultation in relation to the Code's dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website atwww.thetakeoverpanel.org.uk.


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