FORM 8.5 (EPT/RI)

PUBLIC DEALING DISCLOSURE BY AN EXEMPT PRINCIPAL TRADER WITH RECOGNISED INTERMEDIARY STATUS DEALING IN A CLIENT-SERVING CAPACITY

Rule 8.5 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Name of exempt principal trader:

Deutsche Bank AG

(b) Name of offeror/offeree in relation to whose relevant securities the disclosure relates:

Use a separate form for each offeror/offeree

Shire Plc

(c) Name of the party to the offer with which exempt principal trader is connected:

Shire Plc

(d) Date of dealing:

21/07/2014

(e) Have you previously disclosed, or are you today disclosing, under the Code in respect of any other relevant security of any other party to this offer?

YES

2. DEALINGS BY THE EXEMPT PRINCIPAL TRADER

(a) Purchases and sales

Class of relevant security

Purchases/ sales

Total number of securities

Highest price per unit paid/received

GBP

Lowest price per unit paid/received

GBP

5p Ordinary

Purchase

25000

49.71

49.4281

5p Ordinary

Sale

347467

49.95

49.46

(b) Derivatives transactions (other than options)

Class of relevant security

Product description

e.g. CFD

Nature of dealing

e.g. opening/closing a long/short position, increasing/reducing a long/short position

Number of reference securities

Price per unit

GBP

5p Ordinary

CFD

Long

25000

49.65

5p Ordinary

CFD

Long

22625

49.589

5p Ordinary

CFD

Long

14592

49.517048

5p Ordinary

CFD

Long

4763

49.658379

5p Ordinary

CFD

Long

2375

49.589

5p Ordinary

CFD

Long

2375

49.65

5p Ordinary

CFD

Long

2232

49.670108

5p Ordinary

CFD

Long

1101

49.51434

5p Ordinary

CFD

Long

643

49.494953

5p Ordinary

CFD

Long

553

49.51965

5p Ordinary

CFD

Long

390

49.513026

5p Ordinary

CFD

Long

200

49.49255

5p Ordinary

CFD

Short

177500

49.5826

5p Ordinary

CFD

Short

177500

49.571246

5p Ordinary

CFD

Short

25000

49.53945

5p Ordinary

CFD

Short

24735

49.648802

5p Ordinary

CFD

Short

22625

49.60035

5p Ordinary

CFD

Short

11071

49.615893

5p Ordinary

CFD

Short

9166

49.699049

5p Ordinary

CFD

Short

7832

49.71

5p Ordinary

CFD

Short

5243

49.699049

5p Ordinary

CFD

Short

5037

49.71

5p Ordinary

CFD

Short

3786

49.650029

5p Ordinary

CFD

Short

3587

49.699049

5p Ordinary

CFD

Short

3313

49.65101

5p Ordinary

CFD

Short

2375

49.53945

5p Ordinary

CFD

Short

2375

49.60035

5p Ordinary

CFD

Short

1709

49.654429

5p Ordinary

CFD

Short

1453

49.648329

5p Ordinary

CFD

Short

915

49.661934

5p Ordinary

CFD

Short

75

49.649965

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Class of relevant security

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Expiry date

Option money paid/ received per unit








(ii) Exercising

Class of relevant security

Product description

e.g. call option

Number of securities

Exercise date

Exercise price per unit





(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable)





The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(b), copy table 2(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

3. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the exempt principal trader making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

If there are no such agreements, arrangements or understandings, state "none"

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the exempt principal trader making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

Date of disclosure:

22/07/2014

Contact name:

Kelly-Jade Ledwich

Telephone number:

00 44 207 545 8515

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel atmonitoring@disclosure.org.uk. The Panel's Market Surveillance Unit is available for consultation in relation to the Code's dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website atwww.thetakeoverpanel.org.uk.


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