314cfc8c6ebbd63866d2e9.pdf


Matthias Kraemer | Head of Media Relations

Siemens Healthcare GmbH


Unrestricted © Siemens Healthcare GmbH, 2015


Notes and forward-looking statements


This document contains statements related to our future business and financial performance and future events or developments involving Siemens that may constitute forward-looking statements. These statements may be identified by words such as 'expect', 'look forward to', 'anticipate', 'intend', 'plan', 'believe', 'seek', 'estimate', 'will', 'project' or words of similar meaning. We may also make forward-looking statements in other reports, in presentations, in material delivered to shareholders and in press releases. In addition, our representatives may from time to time make oral forward-looking statements. Such statements are based on the current expectations and certain assumptions of Siemens' management, of which many are beyond Siemens' control. These are subject to a number of risks, uncertainties and factors, including, but not limited to those described in disclosures, in particular in the chapter Risks in the Annual Report. Should one or more of these risks or uncertainties materialize, or should underlying expectations not occur or assumptions prove incorrect, actual results, performance or achievements of Siemens may (negatively or positively) vary materially from those described explicitly or implicitly in the relevant forward-looking statement. Siemens neither intends, nor assumes any obligation, to update or revise these forward-looking statements in light of developments which differ from those anticipated.

This document includes - in IFRS not clearly defined - supplemental financial measures that are or may be non-GAAP financial measures. These supplemental financial measures should not be viewed in isolation or as alternatives to measures of Siemens' net assets and financial positions or results of operations as presented in accordance with IFRS in its Consolidated Financial Statements. Other companies that report or describe similarly titled financial measures may calculate them differently.

Due to rounding, numbers presented throughout this and other documents may not add up precisely to the totals provided and percentages may not precisely reflect the absolute figures.


New management of Siemens Healthcare effective from May 1, 2015


Bernd Montag

Chairman of the Executive

Thomas Rathmann

Member of the Executive

Michael Reitermann

Member of the Executive

Management

and CEO

Management

and CFO

Management


May 1st 2015
  • Separation of Siemens Healthcare's business activities into legal entities under the Siemens umbrella

  • Foundation of Siemens Healthcare GmbH in Germany



Buffalo Grove

Elkhart, Mishawaka


Dublin Llanberis Oxford

Hoffman Estates Flanders,

Glasgow

Edgewater

Walpole, Brookfield

Issaquah

Tarrytown

Sudbury


Erlangen, Forchheim

Kemnath Rudolstadt


SeongNam GyeonJu PoHang

Sacramento

Berkeley


Mountain

View Los Angeles

Getafe

Malvern Plymouth Cary Knoxville


Joinville

Marburg


Bangalore Goa


Wuxi Shanghai Shenzhen


Headquarters

Major manufacturing/engineering sites


We innovate to advance human health

R&D spending1) Ratio of R&D expenses as a percentage of revenue1)


1.01 billion 8.1%


Inventions per year Patents per working day


>12,000 1,687>4

patents in total


  1. Fiscal Year 2014

    Unrestricted © Siemens Healthcare GmbH, 2015

    Page 5

    Erlangen, September 29, 2015

    Matthias Kraemer | Healthcare


    Key Financials

    Key financials

    Revenue by Region2)


    FY 2014

    € 12.1 bn

    € 11.7 bn

    € 2.1 bn

    17.7%


    Orders Revenue

    Profit (w/o PPA amortization) in % of revenue


    Asia, Australia


    27%


    Germany

    7%


    28%


    Europe, CIS3), Africa, Middle East (excl. Germany)


    € 2.0 bn

    17.1%

    Underlying Profit1)

    in % of revenue


    38%


    € 1.9 bn

    Free Cash Flow

    Americas



  2. Profit excl. PPA amortization, transformation charges and other one-time effects Note: All data Healthcare excluding Hospital Information Systems and Audiology

  3. FY 2014 external revenue by location of customer

  4. Commonwealth of Independent States


  5. Customers and patients Market


    Demographics:

    Ageing and age-related diseases

    Healthcare business


    Cost pressure, industrialization of healthcare


    Shortage of qualified HC professionals

    Consolidation



    Consumerization, patient centricity


    Regulatory environment


    Accountable care, outcome focus


    Knowledge-based healthcare: Connectivity, big data


    Technology


    Pace of scientific advance


    Expected impact on Siemens HC business: Positive Negative


    Interventional

    Angiography Mammography Molecular Imaging Imaging Software



    Computed Ultrasound

    Tomography Imaging

    Women's health

    Radiation therapy

    Oncology Neurology

    Radiology


    Urology


    Cardiology


    Surgery


    Intensive care unit


    Molecular Testing


    Point-of-Care Testing


    Magnetic

    EmergencyLaboratory

    X-ray Imaging

    Resonance Imaging Hemostasis and Hematology Testing


    Technology

    • MRI relies on the principle that the hydrogen atoms in the human body possess magnetic properties: Exposed to the magnet in the MRI system, the nuclei of these atoms align with the magnetic field, like the needle of a compass with the earth's magnetic field

    • The MRI system generates a second electro- magnetic field by transmitting high-frequency radio waves. These waves meet the nuclei of the atoms and set them in motion

    • If the waves are turned off, the atoms return to their initial position within the magnetic field.

    • A computer converts the data and uses them to generate tomograms, or slice images

    As they do so, they release some of the energy that they have absorbed from exposure to the high-frequency waves. This released energy is measured by highly sensitive receiver coils, and suitable techniques can be used to pinpoint its origin

    Pros

    No ionizing radiation Painless

    Results

    High resolution 2D or 3D imaging



    Good soft tissue contrast ofhuge body parts

    Multiplanar Use cases

    Difficult fractures, joint problems,

    Cons Time effort soft tissue examinations, tumors, Mightneed contrast media MRI-Angiography, Brain MRI

    Noise


    Copyright: Siemens MedArchiv

    Market position #1 globally

    Copyright: Siemens MedArchiv



    Unrestricted © Siemens Healthcare GmbH, 2015

    Page 9

    Erlangen, September 29, 2015

    Matthias Kraemer | Healthcare


    Technology

    • CT measures the attenuation of X-rays within the tissue, visualizing the inside of the body as tomograms - slice images - on a screen

    • A measurement system consisting of the X-ray tube and the opposite detector is located inside the gantry, which is circling the patient. During this process, the tube transmits a fan-shaped X-ray beam, which is weakened less by soft tissue than by firmer tissue (bones) as it passes through the body

    • When they reach the detector, the X-rays hit a 'scintillator' - Siemens uses a highly

    • The computer translates the measurements into individual section images or even a three-

    specialized ceramic mixture - that converts the detected X-rays into light. Photodiodes then convert the light into electricity, and a converter produces digital data from the analog signals and transmits them to the computer for analysis

    dimensional model of the entire body, all

    Pros Free of superimpositions compared to classical X-ray examinations

    Results

    High-contrast 3D pictures of the tissue

    without a noticeable delay

    Fast examinations compared to MR -

    thorax scan in less than one second Use cases

    Heart scan in one heart beat, painless Stroke(Neurology), head or spine

    injuries, internal injuries, diseases of

    Cons Ionizing radiation the respiratory system, tumor follow-up Mightafford injection examinations (Oncology), heart

    ofcontrast medium examinations (Angiography)


    Copyright: Siemens MedArchiv © St. Louis Children's Hospital Barnes-Jewish Hospital, United States Copyright: Siemens MedArchiv

    Market position #1 globally


    Unrestricted © Siemens Healthcare GmbH, 2015

    Page 10

    Erlangen, September 29, 2015

    Matthias Kraemer | Healthcare


    Technology

    • Syngo makes reading, storing, archiving and sharing clinical images easier and more efficient

    • Its innovative technology transforms the power

      of imaging equipment into tangible clinical benefits

    • A common user interface across all modalities streamlines radiologists' work

    • Mobile access capabilities make it possible to view images and findings anywhere

      and on many devices

    • Syngo.via for 3D and advanced visualization software

      • Syngo Dynamics as Cardiovascular Imaging and Information System

      • Syngo Workflow as Radiology Information System (RIS)

      • Syngo.plaza as Picture Archiving

        and Communication Software (PACS)

      • Syngo.share as versatile Vendor Neutral Archive (VNA)

      • Sense

      • Teamplay as first cloud-based healthcare network


        Pros Increased efficiency Increased diagnostic quality

        Common user interface across all modalities


        Cons None


        Results

        Access to image data, increased usability

        Use cases

    • Software for imaging scanners in Angiography, Computed Tomo- graphy, Mammography, Magnetic Resonance, Molecular Imaging etc.

    • Software to connect to current data, comparing benchmarks, and collaborating with healthcare professionals worldwide

    • Software for effective management and sharing of clinical image data, multimedia data, radiological studies and clinical documents

    • Software to support integrated, cross-enterprise healthcare networks by providing medical information


      Technology

      • Like light, X-rays are electromagnetic waves

      • Radiation is generated in an X-ray tube when electrons from an incandescent wire, the cathode, are beamed at a specific metal part known as the anode

      • When the electrons strike the anode,

        X-ray radiation is generated. As they pass


        Pros Low cost

        Available almost in every clinic Still most often used

        No physician needed to produce X-ray images

        Bone density is measurable


        Results

        2D and even 3D pictures


        Use cases

        Cardiovascular diseases e.g. heart attack (angiography), fractures (radiography and mobile radiography), ortho, trauma,

        through the body, the rays are absorbed to different degrees

      • Bones are so dense that they weaken the rays, leaving a bright, clear image

      • Other kinds of tissue allow more of the radiation to pass through

      • The X-ray image is either captured on film or an electronic sensor converts it into

        a digital image

      • The short-wavelength rays are invisible to the human eye

        Cons

        Ionizing radiation

        Image quality less compared to CT or MR Not suitable for pregnant women

        Copyright: Siemens MedMuseum

        Soft tissue is not seen properly

        surgery, CT, mammography (women's

        health), urology, fluoroscopy


        Technology

    • Ultrasound uses high-frequency sound waves

    • The transducer emits waves and receives their echo reflected from the tissue

    • This echo is calculated into grey values

      for real-time images also for moving organs like the heart

    • Using Doppler sonography, blood flow velocity may be determined and the flow relationship in vessels displayed. As a result, information can be obtained regarding constrictions, occlusions, and standard variants in vessels and the heart

    • Wide-area panoramic displays and three- and four- dimensional images can be generated on the computer in order to better analyze complex anatomical structures


      Pros


      Cons


      No radiation (can be used for children and pregnant women)

      Affordable and in most clinics available technology

      Easy to use


      Can't percolate bone or air (lung) Difficult to percolate technically difficult patients


      Results

      Ultrasound delivers real-time images in 2D, 3D or 4D

      Use cases

      Pregnancy, fetus scans (Gynecology); heart examinations; thyroid glands; gallstones; kidneys, nerves, blood vessels

      • almost all organs, except lung and bones


        Technology

        • Performed to view blood vessels after injecting them with a radiopaque dye that outlines them on X-Ray. This helps to detect abnormalities including narrowing (stenosis) or blockages in the blood vessels (occlusions)

        • Angiography is used for diagnosis and treatment of arteries, veins, and lymphatic vessels,

          as well as the heart chambers

        • If a vessel is constricted, the contrast agent helps in locating the stenosis and detecting to which percentage the lumen of the vessel is occluded

        • When diagnosing tumors, angiography can be used to show the blood supply of the tumor

        • The origin of internal bleeding, such as a damaged vessel, can be precisely located

        • In interventional angiography imaging tools are used for minimally invasive procedures including angioplasty and embolization


      Pros


      Cons


      Image guidance in interventional procedures

      Diseases can be diagnosed and treated using minimally invasive procedures

      Enables treatment even for very old or sick people Less scar tissue

      Faster healing


      Ionizing radiation

      Contrast media can further damage e.g. the kidney Known allergies to contrast media with some diseases

      Internal bleedings as complications of puncturing an artery


      Results

      • Digital subtraction angiography (DSA) to 'subtract' bones and other organs to better see the vessels

      • Image guidance in interventional procedures

      • Check for successful treatment

      Use cases

      Cardiac catheterization during coronary angiography (e.g. chronical heart disease); aortography

      (e.g. aortic aneurysms/dissection); cerebral angiography to visualize vessels in the brain (e.g. stroke, aneurysms, thrombectomy); Angiography of the leg and pelvic vessels (e.g. diabetes); Chemo- embolization of tumor feeding vessels


      Copyright:

      Dr. Azam Ahmed, University of Wisconsin, Madison, USA


      Technology

    • Single Photon Emission Computed Tomography (SPECT), Positron Emission


      Pros


      Detecting diseases at very early stage e.g. cancer or Alzheimer's


      Results

      Molecular imaging procedures are able to

      Tomography (PET), Magnetic Resonance,

      Optical Imaging and Ultrasound

      Monitoring cancer therapy image different biological processes of organs at the cellular level and thus can

    • Probes known as imaging biomarkers (i.e., peptides, radiopharmaceuticals, fluorescents) are injected into the body to help display particular targets or pathways

    • Through chemical interactions with their surroundings, imaging biomarkers alter the image according to molecular changes that occur within the area of interest

    • This level of functional imaging displays, for instance, increased metabolic activity that is typical for malignant tumors like recurrent prostate cancer

    • The addition of CT to either PET or SPECT provides the anatomical 'map' for pinpointing the exact location of disease in the body, to match their metabolic or functional information

      Cons

      Without CT or MR no anatomical structure visible

      Very expensive and limited availability

      Injection of imaging biomarkers such as radiopharmaceuticals

      provide earlier and more precise evaluation of disease

      Use cases

      PET imaging is used for cardiac indications like coronary artery disease and helps detect most types of cancers and how much they have spread in the body. PET also provides diagnostic information on neurological disease.

      The main indications for SPECT are detection of tumors at a very early stage, sentinel nodes and infections, as well as cardiac and coronary vessel pathologies


      Point-of-Care (POC)

      Chemistry/Immunoassay, Hematology, Hemostasis

      Automation, Diagnostics IT

      • (Blood) samples testing is performed close to the patient

      • Tests outside the traditional central laboratory and in a very short time

      • Pocket ultrasound systems as Point-of-Care system, mostly used in obstetrics

      • No need to wait for results from a lab

      • Easy to handle and cost efficient

      • Improving the workflow in physician's offices

    Use cases

    Routine physical exam (urine analysis),

    diabetes management (blood glucose monitoring), emergencies or during an operation (blood gas analysis), gynecology

    • Testing of body liquids such as urine or blood tests as well as the measurement of specific chemicals

    • Immunoassays as biochemical tests that measure the presence or concentration of molecules in the blood through the use of an antibody or immunoglobulin

    • Early proof of a broad range of diseases without invasive examinations

    • Reliable, fast and cost efficient analysis and ongoing observation of the course of diseases

    Use cases

    Fertility testing, allergy, anemia, cardiac and tumor markers, diabetes management,

    control of kidney function, urinary tract infections, bone metabolism, inflammations

    • Systems that can do multiple tests at once and then extrapolate the information

    • Moving samples to and from multiple analyzers, automatically performing additional tests or cancelling previously ordered tests according

      to pre-programmed protocols

    • Allows caregivers to make faster and more timely treatment decisions for patients

    • High initial capital investment, but immediate returns on investment from improved lab efficiency, throughput and capacity

    Use cases

    All four diagnostic disciplines of chemistry, immunoassay, hematology and hemostasis on a single automated track


    More than 200,000 instruments installed worldwide, from hospitals to physician offices to the most remote locations in the world like the Australian Outback

    More than 900 million patients tested per year, more than 7 billion tests provided per year

    More than 1,300 installed track-based automation systems world-wide, more than any other company

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