NEW YORK, December 27, 2016 /PRNewswire/ --

The Major Drug Manufacturers space is engaged in the research, creation, and manufacturing of therapeutic drugs. This Healthcare sector is characterized by substantial research and development costs, and is heavily regulated by world governments. For today, Stock-Callers.com directs its attention to: Provectus Biopharmaceuticals Inc. (NYSE MKT: PVCT), Novartis AG (NYSE: NVS), TherapeuticsMD Inc. (NYSE MKT: TXMD), and Tonix Pharmaceuticals Holding Corp. (NASDAQ: TNXP). Learn more about these stocks by downloading their comprehensive and free reports at:

http://stock-callers.com/registration

Provectus Biopharma  

Knoxville, Tennessee-based Provectus Biopharmaceuticals Inc.'s shares finished Friday's session 21.53% higher at $0.02. A total volume of 11.51 million shares was traded, which was above their three months average volume of 3.87 million shares. The stock is trading below its 50-day moving average by 51.27%. Moreover, shares of Provectus Biopharma, which engages in developing ethical pharmaceuticals for oncology and dermatology indications, have a Relative Strength Index (RSI) of 39.85.

On December 22nd, 2016, Provectus Biopharmaceuticals announced acceptance of two abstracts for poster presentations at international oncology conferences in February 2017. Both abstracts describe data from the Company's phase 1 study of PV-10 in tumors of the liver. The first abstract, titled "Percutaneous Rose Bengal as an Ablative Immunotherapy for Hepatic Metastases," to be presented at Clinical Interventional Oncology (CIO) on February 4th-5th, 2017, in Hollywood, Florida, focuses on outcome in patients with colorectal cancer that has metastasized to the liver. The second abstract, titled "Intralesional Rose Bengal as an Ablative Immunotherapy for Hepatic Tumors," to be presented at the 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL) on February 15th-19th, 2017, in Shanghai, China, focuses on outcome in patients with hepatocellular carcinoma. PVCT complete research report is just a click away and free at:

http://stock-callers.com/registration/?symbol=PVCT Novartis  

Shares in Basel, Switzerland headquartered Novartis AG ended the day 0.11% higher at $71.85 with a total trading volume of 1.47 million shares. The stock has advanced 4.42% in the last month. The Company's shares are trading 0.48% above their 50-day moving average. Moreover, shares of Novartis, which researches, develops, manufactures, and markets a range of healthcare products worldwide, have an RSI of 58.47.

On December 20th, 2016, Novartis announced that it has entered into a definitive agreement for the acquisition of Encore Vision, Inc., a privately-held company in Fort Worth, Texas, USA, focused on the development of a novel treatment in presbyopia. This acquisition would add a first-in-class disease modifying topical treatment for presbyopia to the Novartis ophthalmology pipeline, providing a potentially disruptive innovation to patients in a new therapeutic area of high unmet need and high prevalence. The transaction is subject to customary closing conditions, including regulatory approval. The financial details of this transaction were not disclosed. The complimentary report on NVS can be downloaded at: http://stock-callers.com/registration/?symbol=NVS

TherapeuticsMD  

Boca Raton, Florida headquartered TherapeuticsMD Inc.'s stock rose 4.73%, closing the session at $5.98 with a total trading volume of 1.79 million shares. Shares of the Company, which operates as a women's health care product company, are trading 2.64% below their 50-day moving average. The stock has an RSI of 48.13.

On December 5th, 2016, TherapeuticsMD announced positive top-line results from its pivotal phase 3 Replenish Trial of TX-001HR, an investigational bio-identical hormone therapy combination of 17ss-estradiol and progesterone in a single, oral softgel, for the treatment of moderate to severe vasomotor symptoms (VMS) due to menopause in post-menopausal women with an intact uterus. The Replenish Trial evaluated four doses of TX-001HR and placebo in 1,835 post-menopausal women between 40 and 65 years old. Sign up for your complimentary research report on TXMD at:

http://stock-callers.com/registration/?symbol=TXMD Tonix Pharma  

On Friday, shares in New York-based Tonix Pharmaceuticals Holding Corp. finished the session 3.23% lower at $0.48. A total volume of 914,673 shares was traded. The stock has surged 26.22% in the last month. The Company's shares are trading above their 50-day moving average by 2.25%. Furthermore, shares of Tonix Pharma, which develops medicines for common disorders of the central nervous system, have an RSI of 55.25.

On December 19th, 2016, Tonix Pharmaceuticals announced that the US FDA has granted Breakthrough Therapy designation to TNX-102 SL* for the treatment of posttraumatic stress disorder (PTSD). The benefits of Breakthrough Therapy designation include the eligibility for priority review of the New Drug Application (NDA) within 6 months instead of 10 months and rolling submission of portions of the NDA. Tonix held a successful End-of-Phase 2/Pre-Phase 3 meeting with the FDA in Q3 2016, based on positive data from its 12-week randomized, double-blind, placebo-controlled Phase 2 AtEase study. Tonix plans to begin enrolling patients into its first Phase 3 study, the HONOR study, in Q1 2017 after receiving FDA agreement on the study design and interim analysis plan. Get free access to your research report on TNXP at:

http://stock-callers.com/registration/?symbol=TNXP

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