Log in
E-mail
Password
Remember
Forgot password ?
Become a member for free
Sign up
Sign up
Settings
Settings
Dynamic quotes 

4-Traders Homepage  >  Equities  >  Euronext Bruxelles  >  UCB    UCB   BE0003739530

UCB (UCB)

Real-time Quote. Real-time Tradegate - 08/25 06:40:59 pm
71.995 EUR   -1.24%
08/19 UCB : Transparency notification
08/18 UCB : Transparency notification
08/14 UCB : U.S. District Court confirms validity of patent for UCB's Vimp..
SummaryQuotesChartsNewsAnalysisCalendarCompanyFinancialsConsensusRevisions 
News SummaryMost relevantAll newsSector news 

UCB : Sponsors Data Presentations on Epilepsy and Vimpat® (lacosamide) C-V at the 64th Annual Meeting of the American Academy of Neurology

share with twitter share with LinkedIn share with facebook
share via e-mail
0
04/18/2012 | 06:52pm CEST

Guide to UCB-sponsored epilepsy data, including updated analysis for Vimpat® patient-reported health-related quality of life

Brussels (Belgium), 18th April 1800 CEST - UCB, a leading biopharmaceutical company committed to the development of new epilepsy treatments and research, will sponsor 10 sets of key epilepsy data at the 64th Annual Meeting of the American Academy of Neurology (AAN) in New Orleans from April 21-28. The data comprise several posters examining the use of the antiepileptic drug (AED) Vimpat® (lacosamide) C-V, including updated health-related quality of life analysis from pooled open label extension trials.

"UCB is committed to advancing research to better understand the clinical profile of Vimpat®. The research we will present at AAN encompasses several lacosamide studies that measure patient-reported seizure frequency and health-related quality of life over the long-term," said Dr. James Zackheim, PhD, Senior Medical Director, Central Nervous System Business Unit, UCB, Inc.

Vimpat® is indicated as an add-on therapy for the treatment of partial-onset seizures in adults with epilepsy. The most common adverse reactions reported in pivotal trials and occurring in 10 percent or more of Vimpat®-treated patients, and greater than placebo, were dizziness, headache, nausea and diplopia. Additional important safety information for Vimpat® is available at the end of the press release.

Following is a guide to UCB-sponsored posters for Vimpat® and epilepsy being exhibited during AAN. For more information please contact Andrea Levin at 404.483.7329or Andrea.Levin@ucb.com.

UCB-Sponsored Posters

Vimpat® (lacosamide) C-V Posters:
1. Lacosamide as Add-On to Monotherapy in Patients with Partial-Onset Seizures: Interim Results of the Post-Marketing VITOBA Study (VImpaT added to One Baseline AED)
P06.126; Poster Session VI: Thursday, April 26, 7:30 a.m. - 12:00 p.m.

2. Long-Term Adjunctive Lacosamide in Patients with Focal Epilepsy: Seizure Severity and Quality of Life
P01.075; Poster Session I: Monday, April 23, 2:00 p.m. - 6:30 p.m.

3. Seizure Severity, Health-Related Quality of Life and Health Status Reported by Patients During Long-Term Treatment with Lacosamide: Analysis of Pooled Open-Label Data
PD3.008; Poster Session III: Tuesday, April 24, 2:00 p.m. - 6:30 p.m.

4. Lacosamide Added to Concomitant AEDs Grouped by Mechanism of Action: Impact on Patient-Reported Quality of Life in Pooled Phase II/III Trials
P06.114; Poster Session VI: Thursday, April 26, 7:30 a.m. - 12:00 p.m.

5. Evaluation of Long-Term Treatment with Lacosamide for Partial-Onset Seizures: A Pooled Analysis of Open-Label Extension Trials
P06.125; Poster Session VI: Thursday, April 26, 7:30 a.m. - 12:00 p.m.

6. Low Lacosamide Plasma Protein Binding in Lacosamide-Naïve Patients
P01.077; Poster Session I: Monday, April 23, 2:00 p.m. - 6:30 p.m.

7. Lacosamide Does Not Alter In Vitro Long-Term Potentiation in Mouse Hippocampal CA1 Area
P05.087; Poster Session V: Wednesday, April 25, 2:00 p.m. - 7:00 p.m.

8. Lacosamide Has No Effect on the Enzymatic Activity of CYP3A4
P01.076; Poster Session I: Monday, April 23, 2:00 p.m. - 6:30 p.m.

Epilepsy Posters:

1. Incidence of Congenital Malformations in Infants Born to Patients With Epilepsy: A Comparison of Pregnancy Registries and Cohort Study Data
S56.003; Scientific Sessions: Thursday, April 26, 3:30 p.m.


About Epilepsy
Epilepsy is a chronic neurological disorder affecting approximately 50 million people worldwide and three million people in the U.S. Anyone can develop epilepsy; it occurs across all ages, races, and genders. Uncontrolled seizures and medication side effects pose challenges to independent living, learning, and employment, so the goal of epilepsy treatment is seizure freedom with minimal side effects. In the U.S., more than one million patients continue to have seizures despite initial therapy, and more than 800,000 continue to have seizures despite treatment with two or more therapies. [1],[2]

About Vimpat®
Vimpat® tablets and injection were launched in the U.S. in May 2009 as an add-on therapy for the treatment of partial-onset seizures in people with epilepsy who are aged 17 years and older. Vimpat® injection is a short-term replacement when oral administration is not feasible in these patients. Vimpat® oral solution was launched in June 2010. The availability of the oral tablets, oral solution, and intravenous (IV) injection allows for consistent treatment in a hospital setting.

In the European Union, Vimpat® (film-coated tablets, syrup, and solution for infusion) is approved as adjunctive therapy for the treatment of partial-onset seizures with or without secondary generalization in patients with epilepsy aged 16 years and older. Vimpat® solution for infusion may be used when oral administration is temporarily not feasible.

The maximum approved daily dose for Vimpat® in the European Union and the U.S. is 400 mg/day.

Important safety information about Vimpat® in the U.S.

Warnings and Precautions
Antiepileptic drugs (AEDs) increase the risk of suicidal behavior and ideation. Patients taking Vimpat® should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.

Patients should be advised that Vimpat® may cause dizziness, ataxia, and syncope. Caution is advised for patients with known cardiac conduction problems, who are taking drugs known to induce PR interval prolongation, or with severe cardiac disease. In patients with seizure disorders, Vimpat® should be gradually withdrawn to minimize the potential of increased seizure frequency. Multiorgan hypersensitivity reactions have been reported with antiepileptic drugs. If this reaction is suspected, treatment with Vimpat® should be discontinued.

Vimpat® oral solution contains aspartame, a source of phenylalanine. A 200 mg dose of Vimpat® oral solution (equivalent to 20 mL) contains 0.32 mg of phenylalanine.

Common Adverse Reactions
The most common adverse reactions occurring in

share with twitter share with LinkedIn share with facebook
share via e-mail
0
Latest news on UCB
08/19 UCB : Transparency notification
08/18 UCB : Transparency notification
08/14 UCB : U.S. District Court confirms validity of patent for UCB's Vimpat®
08/05 AMPHASTAR PHARMACEUTICALS : Purchases International Medication Systems (UK) Limi..
07/28 UCB : continues to deliver on its growth strategy
07/25 AMGEN : UCB and Amgen submit biologics license application for Romosozumab to th..
07/05 DAIICHI SANKYO : UCB and Daiichi Sankyo will jointly commercialize lacosamide in..
07/04 UCB : and Daiichi Sankyo announce Japanese approval of lacosamide (brand name VI..
06/10 UCB : bimekizumab demonstrates positive results in early development in patients..
06/08 UCB : commitment to addressing real world patient needs on display at the Annual..
More news
Sector news : Pharmaceuticals - NEC
05:46p FTSE retreats as pharma stocks fall
03:56pDJStocks Fall as Investors Look to Fed's Jackson Hole Meeting
03:12pDJStocks Fall as Investors Look to Fed's Jackson Hole Meeting
03:11pDJStocks Fall as Investors Look to Fed's Jackson Hole Meeting -- 3rd Update
02:15pDJMylan Boosts Price Assistance for EpiPen Amid Backlash
More sector news : Pharmaceuticals - NEC
News from SeekingAlpha
07/31 UCB S.A. 2016 Q1 - Results - Earnings Call Slides
07/31 UCB's (UCBJF) CEO Jean-Christophe Tellier on Q2 2016 Results - Earnings Call ..
07/22 Amgen submits BLA in U.S. for osteoporosis candidate romosozumab
05/28 LANNETT : Structural Benefits Of The Kremers Acquisition: 100+% Upside
03/21 Amgen's romosozumab successful in late-stage study in men with osteoporosis
Advertisement
Financials (€)
Sales 2016 4 047 M
EBIT 2016 736 M
Net income 2016 465 M
Debt 2016 988 M
Yield 2016 1,73%
P/E ratio 2016 28,33
P/E ratio 2017 22,90
EV / Sales 2016 3,75x
EV / Sales 2017 3,45x
Capitalization 14 179 M
More Financials
Chart UCB
Duration : Period :
UCB Technical Analysis Chart | UCB | BE0003739530 | 4-Traders
Full-screen chart
Technical analysis trends UCB
Short TermMid-TermLong Term
TrendsBullishBullishNeutral
Technical analysis
Income Statement Evolution
More Financials
Consensus
Sell
Buy
Mean consensus HOLD
Number of Analysts 17
Average target price 78,8 €
Spread / Average Target 8,1%
Consensus details
EPS Revisions
More Estimates Revisions
Managers
NameTitle
Jean-Christophe Tellier Chief Executive Officer & Executive Director
Gerhard N. Mayr Chairman
Mark D. McDade Chief Operating Officer & Executive Vice President
Detlef Thielgen Chief Financial Officer & Executive Vice President
Iris Loew-Friedrich Chief Medical Officer & Executive Vice President
More about the company
Sector and Competitors
1st jan.Capitalization (M$)
UCB-12.41%15 986
JOHNSON & JOHNSON15.57%324 776
ROCHE HOLDING LTD.-11.47%217 694
NOVARTIS AG-9.45%213 882
PFIZER INC.7.87%211 206
MERCK & CO., INC.18.76%173 462
More Results