Zeltia : The pivotal and registrational trial of Yondelis® in Japan has been positive

The pivotal and registrational trial of Yondelis® in

Japan has been positive

Madrid, 22nd April 2014.- PharmaMar, a biotechnology subsidiary of Grupo Zeltia

- MC:ZEL) has announced that its partner for Japan, Taiho Pharmaceutical Co., LTD., has communicated that the pivotal and registrational study of Yondelis® in soft tissue sarcomas has achieved positive results and therefore Taiho Pharmaceuticals will submit a New Drug Application in the mentioned indication to the Regulatory Authorities in Japan.

Likewise Taiho Pharmaceuticals has communicated PharmaMar that the study data will be presented in ASCO Congress to be held in Chicago from May 30 to June 3,

2014.

About PharmaMar

PharmaMar is a biopharmaceutical subsidiary of Grupo Zeltia; it is a world leader in discovering, developing and marketing marine-based drugs to treat cancer. Yondelis® is the first marine-based antitumour drug. PharmaMar has four other compounds in clinical development: Aplidin®, Zalypsis®, PM01183 and PM060184. PharmaMar also has a rich pipeline of pre-clinical candidates and a major R&D programme.

About Zeltia
Zeltia S.A. is a world-leading biopharmaceutical company specialised in the development of marine- based drugs for use in oncology. Grupo Zeltia consists mainly of the following companies: PharmaMar, the world-leading biotechnology company in advancing cancer care through the discovery and development of innovative marine-derived medicines; GENOMICA, Spain's leading molecular diagnostics company; Sylentis, dedicated to researching therapeutic applications of gene silencing (RNAi); and a chemical division comprising Zelnova and Xylazel, two profitable companies that are leaders in their respective market segments.
Important note
PharmaMar, which is headquartered in Madrid (Spain), is a subsidiary of Grupo Zeltia (Spanish stock exchange: ZEL), which has been listed on the Spanish Stock Exchange since 1963 and on Spain's Electronic Market since 1998. This document is a press release, not a prospectus. This document does
not constitute or form part of an offering or invitation to sell or a solicitation to purchase, offer or

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subscribe shares of the company. Moreover, no reliance should be placed upon this document for any investment decision or contract and it does not constitute a recommendation of any type with regard to the shares of the company.

For more information +34 91 444 4500

This note is also available on the PharmaMar web site: www.pharmamar.comand at Zeltia's website:
www.zeltia.com

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