Log in
E-mail
Password
Remember
Forgot password ?
Become a member for free
Sign up
Sign up
Settings
Settings
Dynamic quotes 
OFFON

4-Traders Homepage  >  News

News :

Latest NewsCompaniesMarketsEconomy & ForexCommoditiesInterest RatesBusiness LeadersFinance ProfessionalsCalendarSectors 
The feature you requested does not exist. However, we suggest the following feature:

SYSTEM RESEARCH : New Findings in Neuroscience Described from University of Louisville (Refinement of Spatial Receptive Fields in the Developing Mouse Lateral...

share with twitter share with LinkedIn share with facebook
share via e-mail
0
05/25/2018 | 06:32pm CEST

New Findings in Neuroscience Described from University of Louisville (Refinement of Spatial Receptive Fields in the Developing Mouse Lateral Geniculate Nucleus Is Coordinated with Excitatory and Inhibitory Remodeling)

By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators discuss new findings in Nervous System Research - Neuroscience. According to news reporting out of Louisville, Kentucky, by NewsRx editors, research stated, "Receptive field properties of individual visual neurons are dictated by the precise patterns of synaptic connections they receive, including the arrangement of inputs in visual space and features such as polarity (On vs Off). The inputs from the retina to the lateral geniculate nucleus (LGN) in the mouse undergo significant refinement during development."

Our news journalists obtained a quote from the research from the University of Louisville, "However, it is unknown how this refinement corresponds to the establishment of functional visual response properties. Here we conducted in vivo and in vitro recordings in the mouse LGN, beginning just after natural eye opening, to determine how receptive fields develop as excitatory and feedforward inhibitory retinal afferents refine. Experiments used both male and female subjects. For in vivo assessment of receptive fields, we performed multisite extracellular recordings in awake mice. Spatial receptive fields at eye-opening were >2 times larger than in adulthood, and decreased in size over the subsequent week. This topographic refinement was accompanied by other spatial changes, such as a decrease in spot size preference and an increase in surround suppression. Notably, the degree of specificity in terms of On/Off and sustained/transient responses appeared to be established already at eye opening and did not change. We performed in vitro recordings of the synaptic responses evoked by optic tract stimulation across the same time period."

According to the news editors, the research concluded: "These recordings revealed a pairing of decreased excitatory and increased feedforward inhibitory convergence, providing a potential mechanism to explain the spatial receptive field refinement."

For more information on this research see: Refinement of Spatial Receptive Fields in the Developing Mouse Lateral Geniculate Nucleus Is Coordinated with Excitatory and Inhibitory Remodeling. Journal of Neuroscience, 2018;38(19):4531-4542. Journal of Neuroscience can be contacted at: Soc Neuroscience, 11 Dupont Circle, NW, Ste 500, Washington, DC 20036, USA. (Society for Neuroscience - www.sfn.org/; Journal of Neuroscience - www.sfn.org/index.aspx?pagename=JournalOfNeuroscience)

Our news journalists report that additional information may be obtained by contacting W. Guido, University of Louisville, Sch Med, Dept. of Anat Sci & Neurobiol, Louisville, KY 40292, United States. Additional authors for this research include G. Govindaiah, I.M. Etherington, W.W. Tschetter and C.M. Niell (see also Nervous System Research - Neuroscience).

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1523/JNEUROSCI.2857-17.2018. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Louisville, Kentucky, United States, North and Central America, Neuroscience, Nervous System Research, University of Louisville.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx LLC

(c) 2018 NewsRx LLC, source Health Newsletters

share with twitter share with LinkedIn share with facebook
share via e-mail
0
Latest news
06:32pSYSTEM RESEARCH : New Findings in Neuroscience Described from University of Louisville (Refinement of Spatial Receptive Fields in the Developing Mouse Lateral...
AQ
06:32pSTUDIES FROM DAIMLER AG YIELD NEW DATA ON CLINICAL TRIALS AND STUDIES (INFLUENCE OF NITROGEN COMPOUNDS ON PEMFC : A Comparative Study)
AQ
06:32pGENEL ENERGY : Kurdish Reg. Gov. pays $47.23M for Tawke field oil ops.
AQ
06:32pCAPITA PLC : - Director/PDMR Shareholding
PR
06:31pDeutsche Bank job cuts being felt from Britain to Australia
RE
06:31pINVESTIGATORS FROM GILEAD SCIENCES ZERO IN ON HIV/AIDS (REPEAT TESTING OF LOW-LEVEL HIV-1 RNA : assay performance and implementation in clinical...
AQ
06:31pStantec Takes Part in $55 Billion in Active Projects, Led by LNG Complex, Other Energy Feats, an Industrial Info News Alert
AQ
06:31pLOWE : 40 employers to participate in Herrera Beutler jobs fair
AQ
06:31pSDIPTECH AB : (publ) signs agreement of acquiring KSS Klimat- & Styrsystem AB
AQ
06:31pPEPSICO : Announces Definitive Agreement to Acquire Bare Snacks, Expanding Better-For-You Portfolio into Baked Fruit and Vegetable Snacks
PR
Latest news
Advertisement