The board of directors of the Sirnaomics Ltd. announced that Dr. Xiaochang Dai (Dr. Dai) has resigned from the position as the Chief Strategy Officer of the Group with effect from May 17, 2024 due to his personal reasons. Dr. Dai will remain as an executive Director and has agreed to serve as the Senior Advisor for drug development and commercialization of the Group. Dr. Dai has confirmed that he had no disagreement with the Board and there were no other matters relating to his resignation as the Chief Strategy Officer of the Group that need to be brought to the attention of the shareholders of the Company or The Stock Exchange of Hong Kong Limited.