Not intended for U.S. and UK Media - American Association for Cancer Research (AACR) 108th Annual Meeting: -- Phase II Copanlisib Data Show Durable Tumor Response in Indolent Non-Hodgkin’s Lymphoma -- Copanlisib achieves objective tumor response rate of 59% in indolent Non-Hodgkin’s Lymphoma (iNHL) patients with a manageable safety profile in CHRONOS-1 study / Data to be featured in an oral presentation in a Clinical Trials session on April 4 at AACR / Bayer in discussion with the U.S. Food and

Bayer AG is one of the world's leaders in designing, producing, and marketing pharmaceutical products and agrochemicals. Net sales are distributed by product family as follows: - agrochemicals (48.8%): herbicides, fungicides, insecticides, etc.; - pharmaceutical products (38%): intended for the prevention and treatment of cardiovascular and respiratory diseases, diabetes, nervous system disorders, etc.; - OTC products and nutritional supplements (12.7%); - other (0.5%). Net sales are distributed geographically as follows: Germany (5.1%), Switzerland (1.2%), Europe-Middle East-Africa (23.2%), the United States (30.6%), North America (3.5%), China (7.6%), Asia-Pacific (10%), Brazil (10.4%) and Latin America (8.4%).