Imugene lead product HER-Vaxx patent application receives US Notice of Allowance

• Imugene's biggest intellectual property milestone

• Patent will give method of composition and method of use protection to 2030

Me l b o u r n e , 2 9 Ju l y 2014 : Australian biopharmaceutical company Imugene Limited (ASX:IMU) has received a Notice of Allowance from the United States Patent and Trademark Office (USPTO) for Patent Application 13/389419 (2030 expiry) which protects its HER-Vaxx cancer immunotherapy, currently in development for gastric cancer.
The patent titled "Multiepitope Vaccine for HER2/Neu-associated Cancers" protects the method of composition and method of use of Imugene's HER-Vaxx for the generation of a therapeutic antibody response against HER-2/neu.
HER-Vaxx is a proprietary therapeutic cancer immunotherapy that stimulates a polyclonal antibody response to HER-2/neu, the same biomarker targeted by the $US6.9 billion per annum drug Herceptin®. HER-Vaxx has successfully completed a Phase 1 study in breast cancer and the next stage of development will be a Phase 2 study in gastric cancer.
Dr Nick Ede, Executive Director Imugene said, "Attaining the key US patent is the biggest milestone for almost every biotechnology company. This adds extra value to HER-Vaxx as this will protect it in the world's largest pharmaceutical market until 2030."
Gastric or stomach cancer is the second most common cause of cancer-related death in the world and the fourth most commonly diagnosed cancer, with over 1,000,000 new cases diagnosed each year.
Co n t a c t :
Paul A Hopper Dr Nick Ede
Executive Chairman Executive Director
+1 858 334 5820 (US) +61 400 642 254
+61 406 671 515 (Australia) nede[at]imugene.com receptogen[at]earthlink.net

Me d i a c o n t a c t : Rudi Michelson

Monsoon Communications

+61 3 9620 3333 rudim[at]monsoon.com.au

Ab o u t I m u g e n e : Imugene (ASX; IMU) is an immuno-oncology biopharmaceutical company developing HER2 +ve gastric and breast cancer immunotherapies. The Company's lead product is HER-Vaxx, a proprietary HER2 +ve cancer immunotherapy that stimulates a polyclonal antibody response to HER-2/neu. HER-2/neu is a known and validated receptor over-expressed on various tumours including gastric, breast, ovarian, lung and pancreatic cancers. HER-Vaxx has successfully completed a Phase I study in breast cancer and the next stage of development will be a Phase II study in gastric cancer. Imugene's corporate headquarters are located in Melbourne, Australia with the scientific team in Vienna, Austria. For more information on Imugene, please visit www.imugene.com

Imugene Limited A.C.N: 009 179 551 Suite 1, 1233 High Street, Armadale, VIC, 3142 Phone: 03 9824 5254 Fax: 03 9822 7735
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