Nicox : Lancement commercial d'AdenoPlus™ aux Etats-Unis PRESS RELEASE



Nicox proposes reverse stock split and convenes Extraordinary Shareholder Meeting

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September 4, 2015. Sophia Antipolis, France.

Nicox S.A. (Euronext Paris: FR0000074130, COX) has convened an Extraordinary Shareholder Meeting on Tuesday October 13, 2015 at 2:00 pm CET, at the Hotel Sophia Country Club - 3550 Route des Dolines,

06410 Biot (Sophia Antipolis), France.

The first resolution submitted to the vote of the shareholders is a delegation of powers to the Board of Directors to carry out a reverse stock split with a 5 to 1 ratio1. Details of the procedure will be communicated on the Company's website (www.nicox.com) when the Board of Directors decides to proceed with the reverse stock split, if it is approved by the General Meeting. Shareholders may contact the Company's

Investor Relations team at communications@nicox.com for any question on the reverse stock split or the voting process.

The second and third resolutions submitted to the vote of the shareholders would replace resolutions voted by the June 3, 2015 shareholder's meeting. The second resolution concerns a revised free share authorization in the context of a revision of French regulations by the Loi Macron in August 2015.

The documents mentioned in articles L.225-115, R. 225-81 and R. 225-83 of the French Code de commerce, including a proxy voting form, will be sent to shareholders upon written request. These documents will also be made available to shareholders at the headquarters and on the website of the Company by September

22, 2015. The text from the notice of convening, which is expected to be published in the Bulletin des

annonces légales obligatoires (BALO) today, is available on the Company's website (in French).

Shareholders may vote by proxy, by internet or by attending the shareholder meeting in person. A guide explaining how to vote, and notably how to vote by internet, will be posted on Nicox's website by September

22, 2015.

In the event the quorum is not reached on the first call, Nicox will convene a shareholder meeting on a second call on Wednesday October 28, 2015 at 2:00 pm CET at the Hotel Sophia Country Club, 3550

Route des Dolines, 06410 Biot (Sophia Antipolis), France.

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1 A reverse stock split is a purely arithmetical operation which does not concern the stock value. This operation aims at dividing the number of shares in circulation by five, whilst the par value is multiplied by five. For instance, a shareholder holding 50 existing Nicox shares before the reverse stock split will hold 10 new Nicox shares after the reverse stock split.

About Nicox

Nicox (Bloomberg: COX:FP, Reuters: NCOX.PA) is an international commercial-stage company focused on the ophthalmic market. With a heritage of innovative R&D, business development and marketing expertise, Nicox is building a diversified portfolio of ophthalmic products that can help people enhance their sight.
Nicox's advanced pipeline features VESNEO™ for the lowering of intra-ocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension, and for which a New Drug Application (NDA) was recently submitted to the FDA by the Company's licensee Valeant. Our pipeline also features: AC-170, a pre-NDA candidate for the treatment of ocular itching associated with allergic conjunctivitis; AzaSite®, a pre-MAA candidate in Europe for bacterial conjunctivitis; and BromSite™, a pre-MAA candidate in Europe for pain and inflammation after cataract surgery. The Group operates directly in six countries, including the United States. It has proprietary commercial operations in Europe's five largest markets complemented by an expanding international network of distributors.
Nicox is headquartered in France and has more than 130 staff worldwide. It is listed on Euronext Paris (Category B: Mid Caps) and is part of the CAC Healthcare, CAC Pharma & Bio and Next 150 indexes.
For more information on Nicox, its commercial products or pipeline, please visit www.nicox.com.

Upcoming 2015 events

Financial and business conferences

Sept.16-18 Kepler Cheuvreux Autumn Conference Paris, France Oct.14 Portzamparc Forum Healthcare Conference Paris, France Nov.5 Société Générale Healthcare Forum Paris, France Nov. 12-13 Bryan Garnier Healthcare Conference Paris, France Nov.20-21 Actionaria 2015 Paris, France Nov.24 Natixis MidCap Conference Paris, France

Scientific conferences

Sept. 23-26

SOE - Congreso Socieda Espanola de Oftalmologia (Booth 139 & 131)

Sevilla, Spain

Oct. 7-10

EVER 2015 - European Association for Vision and Eye Research

Nice, France

Nov. 14-17

AAO - American Academy of Ophthalmology

Las Vegas, US

Nov. 27-30

SOI National Congress

Rome, Italy

Analyst coverage

Bryan, Garnier & Co

Stifel

Invest Securities

Kepler Cheuvreux

Hugo Solvet Max Herrmann Martial Descoutures Alexandra Ralli

Paris, France London, UK Paris, France Paris, France


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Contacts

Nicox Gavin Spencer | Executive Vice President Corporate Development

Caroline Courme | Communication Manager

Tel +33 (0)4 97 24 53 43 | communications@nicox.com

Media Relations

United Kingdom Jonathan Birt


Tel +44 7860 361 746 | jonathan.birt@ymail.com

France NewCap | Nicolas Merigeau

Tel +33 (0)1 44 71 94 98 | nicox@newcap.fr

United States Argot Partners | Eliza Schleifstein

Tel +1 (917) 763-8106 | eliza@argotpartners.com

Investor Relations

Europe NewCap | Julien Perez | Valentine Brouchot
Tel +33 (0)1 44 71 94 94 | nicox@newcap.fr

United States Argot Partners | Melissa Forst

Tel +1 (212) 600-1902 | melissa@argotpartners.com

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This press release contains certain forward-looking statements. Although the Company believes its expectations are based on reasonable assumptions, these forward-looking statements are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those anticipated in the forward-looking statements.

Risks factors which are likely to have a material effect on Nicox's business are presented in the 4th chapter of the 'Document de référence, rapport financier annuel et rapport de gestion 2014' filed with the French Autorité des Marchés Financiers (AMF) on April 10, 2015, which is available on Nicox's website (www.nicox.com).

Nicox S.A.

Drakkar 2 | Bât D | 2405 route des Dolines | CS 10313 | Sophia Antipolis | 06560 Valbonne | France

T: +33 (0)4 97 24 53 00 | F: +33 (0)4 97 24 53 99

www.nicox.com

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