FORM 8.5 (EPT/RI)

PUBLIC DEALING DISCLOSURE BY AN EXEMPT PRINCIPAL TRADER WITH RECOGNISED INTERMEDIARY STATUS DEALING IN A CLIENT-SERVING CAPACITY

Rule 8.5 of the Takeover Code (the "Code")

1. KEY INFORMATION

(a) Name of exempt principal trader:

Deutsche Bank AG London

(b) Name of offeror/offeree in relation to whose relevant securities the disclosure relates:

Use a separate form for each offeror/offeree

Shire Plc

(c) Name of the party to the offer with which exempt principal trader is connected:

Shire Plc

(d) Date of dealing:

26/09/2014

(e) Have you previously disclosed, or are you today disclosing, under the Code in respect of any other relevant security of any other party to this offer?

YES

2. DEALINGS BY THE EXEMPT PRINCIPAL TRADER

(a) Purchases and sales

Class of relevant security

Purchases/ sales

Total number of securities

Highest price per unit paid/received

£

Lowest price per unit paid/received

£

5p Ordinary

Purchase

102882

68.386

51.9

5p Ordinary

Sales

293848

68.386

52

(b) Derivatives transactions (other than options)

Class of relevant security

Product description

e.g. CFD

Nature of dealing

e.g. opening/closing a long/short position, increasing/reducing a long/short position

Number of reference securities

Price per unit

£

5p Ordinary

CFD

Long

186732

53.437508

5p Ordinary

CFD

Long

14371

53.470288

5p Ordinary

CFD

Long

8079

53.509429

5p Ordinary

CFD

Long

7100

53.666197

5p Ordinary

CFD

Long

5711

53.285064

5p Ordinary

CFD

Long

4932

53.3

5p Ordinary

CFD

Long

4211

53.60896

5p Ordinary

CFD

Long

3600

53.72204

5p Ordinary

CFD

Long

2737

53.374856

5p Ordinary

CFD

Long

2054

53.468053

5p Ordinary

CFD

Long

1808

53.330068

5p Ordinary

CFD

Long

1278

52.761095

5p Ordinary

CFD

Long

683

53.574144

5p Ordinary

CFD

Long

490

54

5p Ordinary

CFD

Long

350

53.523028

5p Ordinary

CFD

Short

12755

53.3

5p Ordinary

CFD

Short

9975

53.509356

5p Ordinary

CFD

Short

7977

53.781721

5p Ordinary

CFD

Short

4932

53.3

5p Ordinary

CFD

Short

4690

53.3

5p Ordinary

CFD

Short

3656

53.448001

5p Ordinary

CFD

Short

2275

53.3

5p Ordinary

CFD

Short

1600

53.45286

5p Ordinary

CFD

Short

1156

52.051298

5p Ordinary

CFD

Short

1100

53.484818

5p Ordinary

CFD

Short

668

52.213862

5p Ordinary

CFD

Short

425

52.2

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Class of relevant security

Product description e.g. call option

Writing, purchasing, selling, varying etc.

Number of securities to which option relates

Exercise price per unit

Expiry date

Option money paid/ received per unit








(ii) Exercising

Class of relevant security

Product description

e.g. call option

Number of securities

Exercise date

Exercise price per unit





(d) Other dealings (including subscribing for new securities)

Class of relevant security

Nature of dealing

e.g. subscription, conversion

Details

Price per unit (if applicable)





The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(b), copy table 2(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

3. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the exempt principal trader making the disclosure and any party to the offer or any person acting in concert with a party to the offer:

If there are no such agreements, arrangements or understandings, state "none"

NONE

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the exempt principal trader making the disclosure and any other person relating to:

(i) the voting rights of any relevant securities under any option; or

(ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced:

If there are no such agreements, arrangements or understandings, state "none"

NONE

Date of disclosure:

29/09/2014

Contact name:

Kelly-Jade Ledwich

Telephone number:

020 7545 7804

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel atmonitoring@disclosure.org.uk. The Panel's Market Surveillance Unit is available for consultation in relation to the Code's dealing disclosure requirements on +44 (0)20 7638 0129.

The Code can be viewed on the Panel's website atwww.thetakeoverpanel.org.uk.


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