Washington does not have a veto in the General Assembly. It voted against the draft resolution, along with Israel and eight other countries. The text garnered 153 votes in favor, while 23 countries abstained from the vote.
General Assembly resolutions are not binding but carry political weight, reflecting a global view on the war.
Israel has refused calls for an immediate ceasefire, saying such a call would allow Hamas fighters in the Gaza Strip time to regroup and rearm.
"This resolution does not condemn Hamas. It doesn't even mention Hamas," said Israeli ambassador Gilad Erdan in the General Assembly.
He then held aloft a placard with a telephone number and the name and image of Yahya Sinwar, a Hamas leader in the Gaza Strip.
"If you want a real ceasefire, here is the right address," Erdan said. "Tell Hamas to put down their arms, turn themselves in, and return our hostages. This will bring a complete ceasefire that will last forever."
Israel has bombarded Gaza from the air, imposed a siege and launched a ground offensive in retaliation for an Oct. 7 attack by Hamas that Israel says killed 1,200 people and saw 240 people taken hostage. Gaza's health ministry says 18,205 Palestinians have been killed and nearly 50,000 wounded.
Most of the 2.3 million people in Gaza have been driven from their homes and the United Nations has given dire warnings about the humanitarian situation in the coastal enclave, saying that hundreds of thousands of people are starving.
