May 3 (Reuters) - Wall Street's main indexes opened higher on Friday after a softer-than-expected jobs report revived hopes of the Federal Reserve cutting interest rates this year, while gains in Apple and Amgen on upbeat corporate updates added support.

The Dow Jones Industrial Average rose 483.7 points, or 1.27%, at the open to 38,709.36. The S&P 500 rose 58.6 points, or 1.16%, at the open to 5,122.78, while the Nasdaq Composite rose 306.5 points, or 1.94%, to 16,147.482 at the opening bell. (Reporting by Shristi Achar A in Bengaluru; Editing by Shounak Dasgupta)