PUBLICATION IN ACCORDANCE WITH ARTICLE 14 OF THE BELGIAN LAW OF

2 MAY 2007 REGARDING THE PUBLICATION OF MAJOR SHAREHOLDINGS

(THE "TRANSPARENCY LAW")

GHENT, Belgium, 11 May 2018 - Ablynx [Euronext Brussels and Nasdaq: ABLX] today announced, in accordance with Article 14 of the Belgian Law of 2 May 2007 regarding the publication of major shareholdings in issuers whose securities are admitted to trading on a regulated market (the "Transparency Law"), that it received a notification of shareholdings from BlackRock, Inc. on 8 May 2018.

BlackRock, Inc. (taking into account the holdings of its subsidiary undertakings) notified Ablynx that on 4 May 2018 it has downward crossed the 3% threshold of voting rights attached to shares for BlackRock, Inc. and downward crossed the 5% threshold of the total holding in voting rights for BlackRock, Inc.

BlackRock, Inc. now holds a total of 3,323,360 voting securities of Ablynx, representing 4.41% of the current 75,406,551 outstanding voting rights of Ablynx (versus 5.12% notified previously on 7 May 2018).

The most recent notification contains the following information:

  • - Reason for the notification: acquisition or disposal of voting securities or voting rights

  • - Notification by: a parent undertaking or a controlling person

  • - Persons subject to the notification requirement:

Name

Address (for legal entities)

BlackRock, Inc.

55 East 52nd Street, New York, NY, 10055, U.S.A.

BlackRock (Netherlands) B.V.

Rembrandt Tower, 17th floor, Amstelplein, Amsterdam, Netherlands

BlackRock Advisors (UK) Limited

12 Throgmorton Avenue, London, EC2N 2DL, U.K.

BlackRock Advisors, LLC

100 Bellevue Parkway, Wilmington, DE, 19809, U.S.A.

BlackRock Asset Management Canada Limited

161 Bay Street, Suite 2500, Toronto, Ontario, M5J 2S1, Canada

BlackRock Asset Management Deutschland AG

Max-Joseph-Straße 6, Munich, 80333, Germany

BlackRock Financial Management, Inc.

55 East 52nd Street, New York, NY, 10055, U.S.A.

BlackRock Fund Advisors

400 Howard Street, San Francisco, CA, 94105, U.S.A.

BlackRock Institutional Trust Company, National Association

400 Howard Street, San Francisco, CA, 94105, U.S.A.

BlackRock Investment Management (Australia) Limited

Level 37, Chifley Tower, 2 Chifley Square, Sydney NSW 2000 Australia

BlackRock Investment Management, LLC

1 University Square Drive, Princeton, NJ, 8540, U.S.A.

  • - Transaction date: 4 May 2018

  • - Threshold that is crossed: 5% (of the total holding)

  • - Denominator: 75,406,551

-

Details of the notification:

Name of select subsidiaries of BlackRock

% of voting rights

% of voting rights held through financial instruments*

Total of both

BlackRock (Netherlands) B.V.

0.01%

0.01%

BlackRock Advisors (UK) Limited

0.83%

0.04% 1

0.87%

BlackRock Asset Management Canada Limited

0.01%

0.01%

BlackRock Asset Management Deutschland AG

0.25%

0.25%

BlackRock Fund Advisors

0.85%

0.85%

BlackRock Institutional Trust Company, National Association

0.52%

0.11% 2

0.63%

BlackRock Investment Management (Australia) Limited

0.00%

0.00%

BlackRock Investment Management, LLC

0.80% 2

0.80%

BlackRock Advisors, LLC

0.33%2

0.33%

BlackRock Financial Management, Inc.

0.67% 2

0.67%

TOTAL

2.46%

1.94%

4.41%

* Type of financial instrument: 1'Securities lent' and 2'Contract for Difference'

  • - Chain of controlled undertakings through which the holding is effectively being held: Please see the full chain of control in the Transparency Notification.

  • - Additional information: The disclosure obligations arose due to voting rights attached to shares going below 3% and the total holding in voting rights going below 5%.

A full version of the transparency notification is available on Ablynx website, under the sectionInvestors.

The Articles of the Association of Ablynx NV provide for shareholders notification threshold of 3%, 5% or a multiple of 5% of the total number of existing voting rights.

About Ablynx

Ablynx is a biopharmaceutical company engaged in the development ofNanobodies,proprietary therapeutic proteins based on single-domain antibody fragments, which combine the advantages of conventional antibody drugs with some of the features of small-molecule drugs. Ablynx is dedicated to creating new medicines which will make a real difference to society. Today, the Company has more than45 proprietary and partneredprogrammes in development in various therapeutic areas including inflammation, haematology, immuno-oncology, oncology and respiratory disease. The Company has collaborations with multiple pharmaceutical companies including AbbVie; Boehringer Ingelheim; Eddingpharm; Merck & Co., Inc., Kenilworth, New Jersey, USA; Merck KGaA; Novo Nordisk; Sanofi and Taisho Pharmaceuticals. The Company is headquartered in Ghent, Belgium. More information can be found onwww.ablynx.com.

On 29 January 2018, Sanofi made an offer to acquire all of Ablynx's outstanding ordinary shares (including shares represented by American Depository Shares (ADSs), warrants and convertible bonds) at a price of €45 per share, which represents an aggregate equity value of approximately €3.9 billion. The proposed transaction was unanimously approved by both the Sanofi and Ablynx Board of Directors. The initial tender offer commenced on 4 April 2018 and expired on 4 May 2018, subject to extension. Sanofi has published an offer document in which it set out the full details of its tender offer, and the Board of Directors of Ablynx published a response memorandum ('memorie van antwoord'), in which it set out its position on the tender offer.

For more information, please contact:

Ablynx

Dr Edwin Moses CEO t: +32 (0)9 262 00 07 m: +32 (0)473 39 50 68 e:edwin.moses@ablynx.com

@AblynxABLX

Ablynx media relations:

Lies Vanneste Director IR t: +32 (0)9 262 0137 m: +32 (0)498 05 35 79 e:lies.vanneste@ablynx.comConsilium Strategic Communications Mary-Jane Elliott, Philippa Gardner, Sukaina Virji t: +44 (0)20 3709 5700 e:ablynx@consilium-comms.com

Joele Frank, Wilkinson Brimmer Katcher Dan Katcher or Joseph Sala t: +1 212-355-4449

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Disclaimer

Ablynx NV published this content on 11 May 2018 and is solely responsible for the information contained herein. Distributed by Public, unedited and unaltered, on 11 May 2018 05:22:05 UTC