On March 1, 2019, Hubert Birner, Ph.D., MBA and Luc Marengere, Ph.D., each members of the Board, notified the Acer Therapeutics Inc. of their intent not to stand for re-election to the Board at the Company’s 2019 annual shareholder meeting on May 17, 2019. The decisions of Mr. Birner and Mr. Marengere not to stand for re-election were not due to any disagreement with the Company on any matter.