Effective April 4, 2019, Michael Fischbach, Ph.D., Halley Gilbert and Kenneth J. Hillan, M.B., Ch.B. resigned as members of the Achaogen, Inc.'s Board of Directors. In connection with the resignation of Ms. Gilbert, formerly a member of the Board's Audit Committee, the Board has appointed Kent Lieginger, Pharm.D., to serve on the Board's Audit Committee. Effective April 15, 2019, Zeryn Sarpangal, the Company's Chief Financial Officer, Principal Financial Officer and Principal Accounting Officer, notified the Company of her resignation from the Company.

In connection with the resignation of Ms. Sarpangal, the Board has appointed Blake Wise, currently Chief Executive Officer of the Company, to serve additionally as the Company's Principal Financial Officer and Principal Accounting Officer effective April 15, 2019.