On March 11, 2019, Eric Teague, the Chief Financial Officer of Adhera Therapeutics, Inc., submitted his resignation as the Chief Financial Officer of the Company and from any other positions (whether as an officer, director or otherwise) that he may hold with the Company or any of its subsidiaries, effective at the close of business on March 22, 2019. Mr. Teague resigned to pursue other business and personal opportunities. The Company has commenced a search to replace Mr. Teague, and it expects to appoint a successor within the coming weeks. The Company anticipates that Mr. Teague will be available to assist in the transition of his ongoing activities on behalf of the Company to his successor following the effective date of his resignation.