American Science and Engineering, Inc. (NASDAQ: ASEI) (AS&E®), a leader in X-ray detection technology, announced today that The Boston Globe has ranked the Company third in this year's Boston Globe Growth 50 and 95th on the Globe 100. AS&E also ranked 24th on the annual 100 Fastest Growing Tech Companies by Business 2.0, a Time, Inc. publication.

?We appreciate this honor from The Boston Globe and Business 2.0,? said Anthony R. Fabiano, President and CEO of AS&E. ?This has been a significant year for us, one in which we've diversified our product offerings and customer base, and won competitive bids for valuable customers, such as NATO and DoD. We continue to be focused on providing cutting-edge technologies to assist governments and corporations worldwide to combat terrorism, drug and weapons smuggling, and trade fraud.?

The Globe 100, now in its 19th year, ranks Massachusetts-based public companies based on financial data from the four quarters ending closest to December 31, 2005, and for corresponding quarters a year earlier. AS&E was ranked third on the Growth 50 list, and 95th on the Top 100 among Massachusetts-based companies whose stock is publicly traded on NASDAQ, New York Stock Exchange or American Stock Exchange. It is the second time that AS&E has been included in the Globe 100.

The Business 2.0 annual ranking of the 100 Fastest Growing Tech Companies (B2 100) was determined by screening more than 2,000 tech companies that have been publicly traded on a U.S. stock exchange for at least three years using financial criteria: growth in revenue, profit, and operating cash flow during the past three years, and the 12-month stock return as of Dec. 31, 2006.

About AS&E®

American Science and Engineering, Inc. (AS&E) is the leading worldwide supplier of innovative X-ray inspection systems. With over 45 years of experience in developing advanced X-ray security systems, the Company's product line utilizes a combination of technologies, including patented Z Backscatter technology, Radioactive Threat Detection (RTD), high energy transmission and dual energy transmission X-ray. These technologies offer superior X-ray threat detection for plastic explosives, plastic weapons, liquid explosives, dirty bombs and nuclear devices. AS&E's complete range of products include cargo inspection systems for port and border security, baggage screening systems for facility and aviation security, and personnel and passenger screening systems. AS&E systems protect high-threat facilities and help combat terrorism and trade fraud, drug smuggling, weapon smuggling, and illegal immigration and people smuggling. AS&E customers include leading government agencies, border authorities, military bases, airports and corporations worldwide, including the U.S. Department of Homeland Security (DHS), U.S. Department of Defense (DoD), U.S. Customs and Border Protection (CBP), Royal Thai Police, HM Revenue & Customs (U.K.) and Hong Kong Customs. For more information on AS&E products and technologies, please visit www.as-e.com.

Safe Harbor Statement. The foregoing press release contains statements concerning AS&E's financial performance, markets and business operations that may be considered ?forward-looking? under applicable securities laws. AS&E wishes to caution readers of this press release that actual results might differ materially from those projected in any forward-looking statements. Factors which might cause actual results to differ materially from those projected in the forward-looking statements contained herein include the following: significant reductions or delays in procurements of the Company's systems by the United States and other governments; disruption in the supply of any source component incorporated into AS&E's products; litigation seeking to restrict the use of intellectual property used by the Company; potential product liability claims against the Company; global political trends and events which affect public perception of the threat presented by drugs, explosives and other contraband; global economic developments and the ability of governments and private organizations to fund purchases of the Company's products to address such threats; and the potential insufficiency of Company resources, including human resources, capital, plant and equipment and management systems, to accommodate any future growth, and future delays in federal funding. These and certain other factors which might cause actual results to differ materially from those projected are detailed from time to time in AS&E's periodic reports and registration statements filed with the Securities and Exchange Commission, which important factors are incorporated herein by reference. AS&E undertakes no obligation to update forward looking statements to reflect changed assumptions, the occurrence of unanticipated events, or changes in future operating results, financial condition or business over time.