Antares Pharma, Inc. announced positive results from a Phase I study for ATRS-1902 for adrenal crisis. The positive results support the advancement of the ATRS-1902 development program to a pivotal clinical study for the treatment of acute adrenal insufficiency, known as adrenal crisis, in adults and adolescents, using its Vai™ novel proprietary rescue pen platform to deliver a liquid stable formulation of hydrocortisone. The results of the Phase I cross-over study met its primary objective showing ATRS-1902 (100 mg) delivered a comparable pharmacokinetic profile to Solu-Cortef® (100 mg), the reference-listed drug, in 32 healthy adults.

The study also demonstrated that ATRS-1902 was safe and well tolerated.