On May 07, 2021, the Board unanimously appointed Dr. Joan W. Miller to the Board. Upon her appointment to the Board of Aptinyx Inc., Dr. Miller became a member of the class of directors with terms expiring at the 2023 Annual Meeting of Stockholders of the Company. On August 25, 2021, the Board appointed Dr. Miller to serve as a member of the Nominating and Corporate Governance Committee of the Board, to replace Patrick Enright as a member of that committee, and to serve as a member of the Science and Medicine Committee of the Board. Dr. Miller currently serves as the David Glendenning Cogan Professor of Ophthalmology and Chair of the Department of Ophthalmology at Harvard Medical School, as well as Chief of Ophthalmology at both Massachusetts Eye and Ear and Massachusetts General Hospital. Dr. Miller is also a member of the National Academy of Medicine, a Gold Fellow of the Association for Research in Vision and Ophthalmology (ARVO), and has served on numerous Scientific Advisory Boards across the biopharmaceutical industry.