H-CYTE, Inc.  announced the publication of its clinical observational study titled, 'Longitudinal Assessment of FEV1 Change Following Autologous Cellular Therapy.' The study, published in the peer-reviewed Journal of Regenerative Medicine & Biology Research, relates to the Company’s innovative autologous treatment, and concludes that patients experienced a statistically significant improvement in pulmonary function at both 3 months and 12 months (FEV1 % predicted) and quality of life (CCQ score) post treatment. The study, which involved 281 participants with COPD (chronic obstructive pulmonary disease). demonstrated that 23% of patients saw an improvement in their lung function by at least 15% from baseline at 3 months post-treatment(FEV1 measures), and 29% of patients saw the same improvement at 12 months post-treatment. At 3 months and 12 months post-treatment, 64% and 67% of participants respectively, experienced a significant quality of life improvement. All participants tolerated the procedure well, and there were no reportable adverse or unexpected events. All participants were able to stay on their physician prescribed medications to manage their COPD. The efficacy, quality of life and safety shown in this study were above and beyond that achieved with their maintenance therapy. The data came from an externally validated patient database. The study design was observational following the intervention and therefore the limitations due to lack of a control group are recognized. To address this, a double blind randomized controlled trial involving the Company’s innovative PRP-PBMC therapy is currently being planned.