Insys Therapeutics Announced earnings guidance for the first quarter of 2016. The company reported preliminary estimated revenues from Subsys (fentanyl sublingual spray) for first quarter of 2016, which reflects a decline in demand. The company expects first quarter will be in the range of $61 million to $62 million.

Estimated revenues for the quarter reflect a decline in demand, as Subsys prescription volumes were down, as well as a reduction in wholesale inventory levels. The company estimates the decrease in wholesale channel inventory levels to be in the range of $7 million.