Advancing health by turning data into clinically meaningful information

IXICO plc

Annual Report & Accounts 2021

IXICO is a trusted partner to the global pharmaceutical industry, supporting their development of new treatments for neurological diseases with unmet clinical needs.

We develop and deploy therapeutic

specific AI algorithms to improve insights

for better outcomes in neurological

clinical trials.

Strategic report

01-30

Governance

31-48

Financial statements

49-92

02

What we do

32

Chairman's statement

50

Independent Auditor's Report

03

How we do it

34

Board of Directors

to the Members of IXICO plc

04

Business model

36

Directors' Report

58

Consolidated Statement of

06

Chief Executive's statement

39

Stakeholder engagement

Comprehensive Income

08

Our five-point strategic growth plan

42

Directors' Remuneration Report

59

Consolidated Statement of Financial Position

10

Market review and opportunities

44

Corporate Governance Report

60

Company Statement of Financial Position

12

Technology and innovation

48

Statement of Directors' Responsibilities

61

Consolidated Statement of Changes in Equity

18

Environmental, Social and Governance

62

Company Statement of Changes in Equity

22

People and culture

63

Consolidated and Company Statements of

24

Financial review

Cash Flows

27

Risk management

64

Notes to the financial statements

27

Principal risks and uncertainties

92

Addresses and advisers

Strategic report

  1. What we do
  2. How we do it
  3. Business model
  1. Chief Executive's statement
  1. Our five-point strategic growth plan
  1. Market review and opportunities
  1. Technology and innovation
  1. Environmental, Social and Governance
  1. People and culture
  1. Financial review
  1. Risk management
  1. Principal risks and uncertainties

Governancereport Strategic

statements Financial

IXICO plcAnnual Report & Accounts 2021

01

Strategic report

What we do

Advanced analytics.

Supporting our clients in their clinical decisions

Our specialist data analytics services and AI technologies are supporting some of the most important neurological clinical trials.

Intelligent insights.

Bringing safe and effective treatment to patients sooner

We are dedicated to enhancing insights in neuroscience.

We measure specific imaging biomarkers to enhance understanding of disease progression and the efficacy and safety of drug candidates.

Find out more in our technology and innovation section on pages 12 to 17

02

IXICO plcAnnual Report & Accounts 2021

How we do it

We help global biopharma clients to

get more from their clinical development

programmes through...

Our services

We provide essential services to biopharmaceutical companies engaged in drug development in neuroscience, providing analysis of medical image data generated in a clinical study. Our extensive experience in defining and delivering biomarker measurements in early-phase clinical development and our bespoke TrialTracker data management platform means we are perfectly placed to deliver robust and regulatory compliant data in all phases of clinical trials.

The outputs from our data analyses are used to improve patient selection, monitor safety and assess clinical

efficacy of the drug being trialled, and to support post-marketing surveillance activities.

Governancereport Strategic

statements Financial

CLINICAL PROGRAMME

SITE SETUP AND

PROJECT

DESIGN AND CONSULTATION

MANAGEMENT

MANAGEMENT

Drawing on our proven neuroscience

We design and deploy harmonised

Our team ensures the efficient

expertise and experience, we enable our

image acquisition protocols across

set-up and ongoing delivery of

clients to optimise biomarker

multiple international sites.

our services to clinical studies.

measurement.

READING &

REGULATORY

DATA MANAGEMENT

PATHWAY

AND QUALITY CONTROL

ANALYSIS

Our service supports deployment

Image and data quality are

We develop and deploy AI data analysis

of imaging biomarkers within

assessed through our proprietary

tools and neuroradiology reading

a regulatory-compliant framework.

digital platform, TrialTracker.

workflows tailored to the study

requirements.

IXICO plcAnnual Report & Accounts 2021

03

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Disclaimer

IXICO plc published this content on 07 December 2021 and is solely responsible for the information contained therein. Distributed by Public, unedited and unaltered, on 17 December 2021 13:38:02 UTC.