The board of directors of JACOBIO PHARMACEUTICALS GROUP CO., LTD. announced that, with effect from March 23, 2023, Dr. Daqing CAI will resign as an independent non-executive Director, the chairman of the audit committee of the Board and a member of the remuneration committee of the Board and the nomination committee of the Board due to pursuit of his other personal affairs. The Board announced that Dr. Bai LU has been appointed as an independent non-executive Director of the Company, and the chairman of the Audit Committee, and a member each of the Remuneration Committee and the Nomination Committee with effect from March 23, 2023. Dr. Lu, aged 65, has long been committed to the research of neurotrophic factors and synaptic plasticity, as well as neurodegenerative and psychiatric diseases, and is an world-renowned neurobiologist.

Dr. Lu is the founder of 4B Technologies (Beijing) Co., Limitedand the co-founder of BioFront Therapeutics (Beijing) Co., Ltd. Dr. Lu also serves as the scientific advisory and a director of Gnosis Healthineer (Beijing) Co., Ltd. since February 2022, providing scientific advice. Dr. Lu served as a researcher in Roche Institute of Molecular Biology and an associate professor in the Department of Biological Sciences of Columbia University from June 1993 to December 1995. Dr. Lu joined National Institutes of Health (NIH) in 1996 and served as the chief of the Neural Development and Plasticity Section of NIH and the associate director of the Division of Cognitive and Mental Health of a trans-NIH translational research program (GCAP) from January 1996 to June 2009.

From July 2009 to October 2013, Dr. Lu served as the vice president of the R&D center of GlaxoSmithKline China. From December 2009 to September 2013, Du. Lu was a guest professor in Tsinghua University and served as the professor of Department of Pharmacology and Pharmaceutical Science and executive vice dean of the Medical School of Tsinghua University from October 2013 to January 2016.

Dr. Lu has been serving as the professor at the School of Pharmaceutical Sciences of Tsinghua University since January 2016. Dr. Lu received a bachelor's degree in Biology at East China Normal University in the PRC in June 1982, a doctoral degree in neurobiology from Cornell University in the United States in June 1990 and then worked in postdoctoral research at Rockefeller University in the United States from July 1990 to June 1993.