KalVista Pharmaceuticals, Inc. presented two posters at the 2022 meeting of the American College of Allergy, Asthma & Immunology in Louisville, Kentucky. The first highlighted new data that reveals the significant impact of HAE attacks on the mental health, daily activities, and quality of life for people living with hereditary angioedema (HAE) receiving either parenterally delivered on-demand only treatment or prophylaxis with on-demand treatment for breakthrough attacks. More than half of people with HAE felt unable to participate in important events or activities, while nearly half felt ‘less than 100% themselves' due to HAE.

The second presentation focused on injection- or infusion-related adverse drug reactions (ADRs) reported in the FDA's Adverse Event Reporting System (FAERS) for currently approved on-demand hereditary angioedema (HAE) therapies. The five most frequently reported ADRs were injection site pain, site swelling, site erythema, access site complications/malfunctions, and incorrect route of product administration.