Sanofi Q1: robust 7% sales growth driven by launches, underpins full-year guidance.

Sales growth of 6.7% at CER and business EPS(1) of EUR1.78

Dupixent sales up 24.9% to EUR2,835 million, on target to deliver EUR13bn in 2024

Pharma launches up 90.5% to EUR606 million, led by Nexviazyme and ALTUVIIIO

Vaccines sales up 5.6%, boosted by Beyfortus

Consumer Healthcare (CHC) up 9.0%, benefiting from the Qunol acquisition in Physical and Mental Wellness and strong Digestive Wellness performance

R&D expenses grew 11.8%, reflecting strategic shift of resources into development

SG&A expenses grew 2.9%, less than sales growth

Business EPS(1) of EUR1.78, down 17.6% reported and 7.4% at CER

IFRS EPS of EUR0.91, down 43.1% reported

R&D transformation advanced further

Three regulatory approvals: new Dupixent indications in the US and Japan and Beyfortus in Japan

Positive phase 3 results for rilzabrutinib in immune thrombocytopenia, a rare disease

Reaffirming increasing pipeline news flow over 2024-2025, including 12 phase 3 data readouts

Corporate Social Responsibility progress

Sanofi Global Health Unit: making a difference for patients in low- and middle-income countries

Cancer and work: Sanofi supporting health and wellbeing in the workplace

Business EPS guidance reiterated

Sanofi expects 2024 business EPS(1) to remain roughly stable excluding the impact of an expected effective tax rate increase to 21% and decrease low single-digit(2) at CER including the higher expected tax rate, barring unforeseen major adverse events. Applying average April 2024 exchange rates, the currency impact on 2024 business EPS is estimated between -5.5% to -6.5%.

Paul Hudson, Chief Executive Officer, commented: 'We are off to an excellent start in 2024, delivering on our strategic priorities and a transformation of our portfolio of medicines and vaccines to become a development-driven, tech-powered biopharma company committed to serving patients and accelerating growth. Continued strong performance by Dupixent and our new launches drove sales growth of seven percent. In parallel, we are delivering on our promise of increased investments in our late-stage pipeline to fully realize its value for patients and Sanofi. We are awaiting regulatory decisions for Dupixent in COPD, a progressive disease with limited effective treatment options. If approved, Dupixent will be the first biologic treatment in COPD. With the robust progress in our portfolio transformation, we reaffirm our financial guidance for 2024.'

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