On November 14, 2019, Soleno Therapeutics, Inc. (Company) amended its agreement with FLG Partners LLC to replace the current FLG Partners service provider, Mr. Jonathan Wolter, with Mr. James Mackaness. Mr. Wolter's has notified the Company of his decision to accept a full-time position at another company and therefore was no longer available to continue his engagement with the Company, effective November 14, 2019. Mr. Mackaness, also a partner at FLG Partners, will serve as the Company's Chief Financial Officer and principal financial and accounting officer, replacing Mr. Wolter effective November 14, 2019.

Mr. Mackaness served as Chief Financial Officer of Invuity, Inc. from August 2015 until its sale to Stryker Corporation in October 2018, remaining with Styker through January 2019 to complete the integration. Previously, he served as Chief Financial Officer and Chief Operating Officer of IRIDEX Corporation from August 2012 to August 2015 and as Chief Financial Officer from Jan 2008 to August 2012.