Targeted Medical Pharma, Inc. announced preliminary findings from an investigator initiated clinical observation of amino acid based medical foods to address specific nutrient deficiencies in children with autism spectrum disease (ASD) symptoms. 26 children ages seven to sixteen were treated for a time period ranging between 30 days and 1 year, who were diagnosed with ASD or suffering from related symptoms including explosive behavior, social isolation, and mood disorder. The investigator reported that children demonstrated significant improvement with regards to decreased disruptive outbursts, improved socialization, improved mood and reduction in drug dose. 100% of patients have responded positively with an average improvement in explosive outbursts at 83% compared to baseline, with patients also demonstrating significant improvements in anxiety and mood regulation.