On April 30, 2019, Thomas L. Harrison, LH.D tendered his resignation from the Board of Directors of Zynerba Pharmaceuticals, Inc., effective April 30, 2019. Dr. Harrison's term would have otherwise expired at the 2019 annual meeting of the stockholders of the Company. Dr. Harrison was the Chair of the Nominating and Corporate Governance Committee and a member of the Compensation Committee. On April 30, 2019, the Board accepted his resignation. Dr. Harrison resigned to focus on his role with Merida Capital Partners in his capacity as Senior Operating Partner. The Board has reduced the number of directors of the Company from eight to seven and has appointed John P. Butler to succeed Dr. Harrison as a member of the Compensation Committee and Pamela Stephenson to succeed Dr. Harrison as Chair of the Nominating and Corporate Governance Committee.