Microsoft Word - 150205_Press Release_FINAL.docx Astellas Announces Personnel Changes and Organization Changes

Tokyo, Japan, February 5, 2015 - Astellas Pharma Inc. (Headquarters: Tokyo; President and CEO: Yoshihiko
Hatanaka) announced the personnel changes and organization changes as below.

1. Appointment of Senior Corporate Executive of Astellas Pharma Inc. effective on April 1, 2015

Name

New Title

Current Title

Masaru Imahori

CEO's Office

Vice President, External Relations

2. Appointment of Corporate Executive of Astellas Phama Inc. effective on April 1, 2015

Name

New Title

Current Title

Hirofumi Seki

CEO's Office

Divisional Senior Vice President, Technology Planning & Administration,

Technology

Yoshihiro Minami

CEO's Office

General Marketing Compliance Officer(Japan)

Kenji Sumi

CEO's Office

General Manager, Tokyo Branch,

Japan Sales & Marketing

Chihiro Yokota

Head of Japan/Asia Development, Global Development,

and Head of Japan Medical Affairs

Head of Japan/Asia Development, Global Development

Makoto Takeuchi

Vice President, External Relations

Divisional Senior Vice President, Research Administration,

Drug Discovery Research

3. Resignation of Senior Corporate Executive of Astellas Pharma Inc. effective on June 17, 2015

Name

Title (effective on April 1, 2015)

Masaru Imahori

CEO's Office

4. Resignation of Corporate Executive of Astellas Pharma Inc. effective on June 17, 2015

Name

Title (effective on April 1, 2015)

Hirofumi Seki

CEO's Office

Yoshihiro Minami

CEO's Office

Kenji Sumi

CEO's Office

5. Appointment of Senior Corporate Executive of Astellas Pharma Inc. effective on June 17, 2015

Name

Title (effective on April 1, 2015)

Mitsunori Matsuda

President, Technology

Yukihiko Sato

President, Japan Sales & Marketing

Chihiro Yokota

Head of Japan/Asia Development, Global Development, and Head of Japan Medical Affairs

Wataru Uchida

President, Drug Discovery Research

Makoto Takeuchi

Vice President, External Relations

6. New Corporate Executive of Astellas Pharma Inc. effective on June 17, 2015

Name

Title (effective on April 1, 2015)

Katsumi Ozawa

General Manager, Tokyo Branch, Japan Sales & Marketing

Kazuhiro Sako

President, Astellas Ireland Co., Ltd

Yukio Matsui

Senior Vice President, Global Marketing Strategy

Nobuaki Tanaka

General Manager, Chiba Branch, Japan Sales & Marketing

Toru Yoshimitsu

Corporate Vice President, Product and Portfolio Strategy

Eisuke Nozawa

Vice President, Regulatory Affairs-Japan, Global Regulatory Affairs

Fumiaki Sakurai

Corporate Vice President, Human Resources

Taiji Sawamoto

Vice President, Clinical Pharmacology, Global Development

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7. Personnel Changes of Astellas Pharma Inc. effective on April 1, 2015

Name

New Title

Current Title

Shigeki Kawabata

Vice President,

Evolving Medical Solutions

Vice President, Pharma Breakthrough

Masaaki Usui

Vice President, Corporate

Communications

President,

Astellas Pharma Australia Pty Ltd

Shinya Suda

Corporate Vice President, Information Systems

(No change: only Japanese organization

name will be changed)

Corporate Vice President, Information Systems

Noriyuki Masuda

Divisional Senior Vice President, Research Administration, DDR

Executive Director, Research Portfolio & Science,

Drug Discovery Research

Minori Saitoh

Vice President,

Drug Repurposing & Application

Management

Senior Director, Research Portfolio & Science,

Drug Discovery Research

Tomonobu Koizumi

Vice President, Regenerative Medicine Labs.,

Drug Discovery Research

Vice President, Bioscience Research Labs., Drug Discovery Research

Rika Hirota

Vice President, Bioscience Research Labs.,

Drug Discovery Research

Senior Director,

Drug Safety Research Labs., Drug Discovery Research

Shigeki Tanaka

Vice President, Japan/Asia Clinical Development 1,

Japan/Asia Development

Vice President,

Asian Development, Development

Toshiyuki Sueyoshi

Vice President, Japan/Asia Clinical Development 2,

Japan/Asia Development

Vice President,

Clinical Development 2, Development

Takuya Oshida

Vice President, Medical Science,

Japan Medical Affairs

Vice President,

Clinical Development 3, Development

Keita Matsui

Vice President, Medical Research,

Japan Medical Affairs

Vice President, Medical Affairs

Naoko Sato

Vice President, Medical Information Center,

Japan Medical Affairs

Vice President, Medical Information Center

Hideki Shima

Divisional Senior Vice President, Technology Planning & Administration,

Technology

President, Astellas Ireland Co., Ltd

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Kazutoshi Ban

Vice President,

Biotechnology Labs., Technology

Senior Director,

Biotechnology Labs., Technology

Tadashi Hakomori

Divisional Senior Vice President, Pharmaceutical Research & Technology

Labs., Technology

Senior Director, Yaizu Technology Center, Astells Pharma Tech Co., Ltd.

Katsumi Ozawa

General Manager, Tokyo Branch,

Japan Sales & Marketing

General Manager, Kyusyu Branch,

Japan Sales & Marketing

Atsuhito Iizumi

General Manager, Kobe Branch,

Japan Sales & Marketing

Executive Director, Yokohama Branch,

Japan Sales & Marketing

Kazuhiko Hayashida

General Manager, Chugoku Branch,

Japan Sales & Marketing

Executive Director, Kyoto Branch,

Japan Sales & Marketing

Kouji Ohba

General Manager, Kyusyu Branch,

Japan Sales & Marketing

General Manager, Chugoku Branch,

Japan Sales & Marketing

Junko Komatsu

Vice President,

Marketing & Business Management, Asia/Oceania Business

Executive Director, Product Marketing, Japan Sales & Marketing

Yukio Matsui

Senior Vice President, Global Marketing Strategy

Vice President,

Marketing & Business Management, Asia/Oceania Business

8. Personnel Changes of Affiliates effective on April 1, 2015

Name

New Title

Current Title

Kazuhiro Sako

President, Astellas Ireland Co., Ltd

Divisional Senior Vice President, Pharmaceutical Research & Technology

Labs., Technology

Charlotte Kremer

Executive Vice President, Medical Affairs

Astellas Pharma Global Development, Inc.

Senior Vice President, Global Medical Affairs,

Astellas Pharma Global Development, Inc.

Bernie Zeiher

President, Global Development, Astellas Pharma Global Development, Inc.

Therapeutic Area Head

and Executive Vice President, Global Development

Astellas Pharma Global Development, Inc.

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9. Appointment of Staff Executive Director of Astellas Pharma Inc. effective on April 1, 2015

Name

New Title

Current Title

Shinya Yano

Staff Executive Director,

Product and Portfolio Strategy

Executive Director,

Product and Portfolio Strategy

Shigenori Kawasaki

Staff Executive Director, Clinical Development Administration,

Japan/Asia Development

Vice President,

Clinical Development 1, Development

Junichiro Honda

Staff Executive Director, Human Resources Development,

Japan Sales & Marketing

Executive Director, Human Resources Development,

Japan Sales & Marketing

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10. Organization Changes

Medical Affairs

In order to strengthen medical functions and organization management in Japan, Medical Affairs Division will be newly established and structuralize existing Medical Affairs and Medical Information. The names of Medical Affairs and Medical Information will change respectively to "Medical Science" and "Medical Information Center". In addition, the functions of Post-marketing Clinical Trial and Post-marketing Survey currently under Medical Affairs will move to under Medical Affairs Division, as newly established "Medical Research".

Pharma Breakthrough

The name of Pharma Breakthrough will change to "Evolving Medical Solutions". The new department name will enforce to reflect the department mission, collaborating with medically and pharmaceutically relevant field and providing the patients with breakthrough solutions.

Regenerative Medicine Labs.

The initial objective of Regenerative Medicine Unit established in April 2014 has been achieved. In order to reinforce research function to evaluate the regenerative medicine programs for clinical studies and in order to create a structure capable for more efficiently and effectively managing external collaboration with regenerative medicine-related authorities etc. as well as internal collaboration, the existing Regenerative Medicine Unit will be reorganized as a new organization named "Regenerative Medicine Labs".

Drug Repurposing & Application Management

Drug Repurposing & Application Management will be created as a new organization which will take a central role in maximization of the outcomes from drug repurposing activities conducted in Drug Discovery Research and appropriate management of research quality assurance in external collaborations as well as internal research in Drug Discovery Research.

Clinical Development

In order to strengthen clinical development functions for global strategic alignment including Asian countries and enabling higher mobility and flexible resource management, Clinical Development 1-3 and Asia Development restructured into "Japan/ Asia Clinical Development 1 and 2".

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For inquiries or additional information
Astellas Pharma Inc. Corporate Communications
TEL: +81-3-3244-3201, FAX:+81-3-5201-7473
http://www.astellas.com/en

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