Microsoft Word - 150205_Astellas Management Structure_FINAL.docx


February 5, 2015

Enhancement of Astellas' Management Structure

TOKYO, February 5, 2015 - Astellas Pharma Inc. (Headquarters: Tokyo; President and CEO: Yoshihiko Hatanaka) announced today that it will enforce its top management committees, top management structure, and global functions and structures effective from April 1, 2015.

1Top Management Committees

The top management committees will be reorganized as below so that we can resiliently respond to accelerating and elaborating environmental changes.

The "Executive Committee (EC)" will be newly established for decision on significant matters in global management of the Astellas group. The EC consists of CEO, as chairperson, CAO & CCO, CFO, CSTO and CMO. The Heads of Drug Discovery Research, Global Development, Technology, Japan Sales & Marketing, Asia/Oceania Business, EMEA operations and Americas operations will join the EC as the extended member for discussion on its related matters upon the chairperson's request.

The "Japan Management Committee (JMC)" will be newly established for decision-making on the significant corporate governance matters of Astellas Pharma Inc. and its affiliates in Japan. The JMC consists of CAO & CCO, as chairperson, and Corporate Vice Presidents of Corporate Planning, Corporate Finance & Control, Human Resources and Legal & Compliance.

The Global Management Committee, the Corporate Administration & Finance Committee and Global Human Resources Committee will be dismantled accordingly.

* CEOChief Executive Officer CAOChief Administrative Officer CCOChief Compliance Officer CFOChief Financial Officer CSTOChief Strategy Officer CMOChief Medical Officer EMEAEurope, Middle East and Africa
The members of each new committee are provided next.

Members

Executive Committee

(EC)

: Member

: Extended Member

Japan Management Committee

(JMC)

CEO

Yoshihiko Hatanaka

Chairperson

CAO & CCO

Yoshirou Miyokawa

Chairperson

CFO

Yasumasa Masuda

CSTO

Kenji Yasukawa

CMO

Sef Kurstjens

President,

Drug Discovery Research

Wataru Uchida

President,

Global Development

Bernie Zeiher

President, Technology

Mitsunori Matsuda

President,

Japan Sales & Marketing

Yukihiko Sato

President,

Asia/Oceania Business

Masatoshi Kuroda

President & CEO,

EMEA Operations

Ken Jones

President & CEO,

Americas Operations

Masao Yoshida

Corporate Vice President,

Corporate Planning

Chikashi Takeda

Corporate Vice President,

Corporate Finance & Control

Yasuo Sakae

Corporate Vice President,

Human Resources

Fumiaki Sakurai

Corporate Vice President,

Legal & Compliance

Okimura Kazunori

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2Top Management Structure

Each top management responsibility will be changed as below, effective from April 1, 2015.

Title

Name

Divisional Responsibilities

CEO

Yoshihiko Hatanaka

Internal Auditing, Drug Discovery Research, Technology, Japan Sales & Marketing, Asia/Oceania Business, EMEA Operations,

Americas Operations, GMS

CAO & CCO

Yoshirou Miyokawa

External Relations, General Affairs, Human Resources, Legal & Compliance,

Executive Office

CFO

Yasumasa Masuda

Corporate Finance & Control,

Accounting & Tax, Corporate Communications, Procurement, Information Systems

CSTO

Kenji Yasukawa

Corporate Planning,

Product and Portfolio Strategy, Business Development, Innovation Management, Evolving Medical Solutions,

Intellectual Property

CMO

Sef Kurstjens

GD, GPV, MA, GRA, GCRQA, GQA

*GMSGlobal Marketing Strategy
GDGlobal Development GPVGlobal Pharmacovigilance MAMedical Affairs GRAGlobal Regulatory Affairs
GCRQAGlobal Clinical and Research Quality Assurance
GQAGlobal Quality Assurance

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3Global Functions and Structures

Enhancement of Global Marketing Strategy

Global Marketing Strategy under Product & Portfolio Strategy will move directly under CEO and the position of Head of Global Marketing Strategy will be newly established. We will provide the patients with the maximized value by enhancing the global market access function, and by promoting the internal collaboration with Medical Affairs, Global Development and regional Marketing.
Yukio Matsui will be appointed to Head of Global Marketing Strategy as of April 1, 2015 and
Head of Global Marketing Strategy will be located in Illinois, the United States.

New Appointment of Head of Global Development

Bernie Zeiher will be newly appointed as Head of Global Development as of April 1, 2015. The current Head of Global Development, Sef Kurstjens, will continue to serve in his role as Chief Medical Officer.

Changes Associated with Medical Affairs Optimization

Medical Affairs is being organized into a new Medical Affairs organization across Astellas, and each regional Medical Affairs head will report on a solid-line basis to Head of Medical Affairs. This change will help optimize the prioritization and use of Medical Affairs resources at Astellas. Charlotte M.E. Kremer will be appointed as Head of new Medical Affairs.

Restructuring of Global Business Development

A single transaction execution function will be created in Business Development, Astellas
Pharma Inc. so that we can align the globally consistent transactional operation.
The alliance management function will be split clearly between global and regional. The global alliance management function will be established in Business Development, Astellas Pharma Inc. and will become a primary contact to global/multi-regional strategic partners. This function will also be responsible for control of issues related to global alliances. The regional alliance management function will be established under the sales and marketing organization in each region and the Japan regional alliance management function will be under Japan Sales &
Marketing, Astellas Pharma Inc.

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Information Systems

The organization of Information Systems will be restructured to consolidate all of world-wide relevant functions and report directly to Head of Information Systems, Astellas Pharma Inc., while some matrix reporting relations will remain in region.

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For inquiries or additional information

Astellas Pharma Inc. Corporate Communications

TEL: +81-3-3244-3201, FAX:+81-3-5201-7473

http://www.astellas.com/en

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