February 5, 2014

Astellas: Reorganization of Astellas' Global Management Structure

TOKYO, February 5, 2014 - Astellas Pharma Inc. ("Astellas"; President and CEO: Yoshihiko Hatanaka) announced today that it will implement the following revisions to its global management structure effective from April 1, 2014:

Global Management Structure

1. Global Development Head will report to Chief Medical Officer ("CMO") from April 1, 2014 (currently reports to CEO).
2. Global Regulatory Affairs Head, Global Clinical and Research Quality Assurance Head, and Global Quality Assurance Head will report to CMO from April 1, 2014 (currently report to QA and RA Head of Astellas Pharma Inc.). Accordingly, the position of QA and RA Head of Astellas Pharma Inc. will be dissolved.

Objective

For the purpose of enhancing global product compliance and the overall synergy with Global Development, Astellas has decided that all Heads of Global Development, GRA*, GCRQA*, and GQA* will report to CMO, while Heads of GPV* and GMA* have already reported to CMO since April 1, 2013.

* GPV: Global Pharmacovigilance GMA: Global Medical Affairs GRA: Global Regulatory Affairs

GCRQA: Global Clinical and Research Quality Assurance

GQA: Global Quality Assurance

Top Management Structure

Along with revisions to the global management structure, new global report line structure will be changed as below, effective from April 1, 2014.

Title

Divisional Responsibilities

President and CEO (Chief Executive Officer)

Internal Auditing, Medical Affairs,

Drug Discovery Research, Technology, Japan Sales & Marketing, Asia/Oceania Business, EMEA Operations, Americas Operations

Executive Vice President, CAO & CCO (Chief Administrative Officer &

Chief Compliance Officer)

External Relations, General Affairs, Human Resources, Legal & Compliance, Executive Office

Senior Vice President and CFO

(Chief Financial Officer)

Corporate Finance & Control, Accounting & Tax,

Corporate Communications, Procurement, Information Systems

Senior Vice President and CSTO (Chief Strategy Officer)

Corporate Planning, Product and Portfolio Strategy, Licensing & Alliances, Innovation Management,

Intellectual Property

CMO

(Chief Medical Officer)

Global Development, GPV, GMA, GRA, GCRQA, GQA

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Global Management Committee

The members of the Global Management Committee will be changed as below, effective from
April 1, 2014.

Global Management Committee

Issues for deliberation: Globally important issues spanning function and geographical regions

President and CEO

Yoshihiko Hatanaka

Executive Vice President, CAO & CCO

Yoshirou Miyokawa

Senior Vice President and CFO

Yasumasa Masuda

Senior Vice President and CSTO

Kenji Yasukawa

CMO and

President, Global Development

Sef Kurstjens

Senior Vice President and

President, Drug Discovery Research

Wataru Uchida

Senior Vice President and

President, Technology

Mitsunori Matsuda

Senior Vice President and

President, Sales & Marketing Japan

Yukihiko Sato

Senior Vice President and

President, Asia/Oceania Business

Masatoshi Kuroda

President and CEO

EMEA Operations

Ken Jones

President and CEO

Americas Operations

Masao Yoshida


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For inquiries or additional information

Astellas Pharma Inc. Corporate Communications

TEL: +81-3-3244-3201, FAX:+81-3-5201-7473

http://www.astellas.com/en

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