In a Pharmacology Research & Perspectives study, the asthma medication montelukast (trade name Singulair) was linked with neuropsychiatric reactions such as depression and aggression, with nightmares being especially frequent in children.

For the study, investigators examined all adverse drug reactions on montelukast in children and adults reported to the Netherlands Pharmacovigilance Center Lareb and the WHO Global database, VigiBase®, until 2016.

'Because of the high incidence of neuropsychiatric symptoms-especially nightmares-after using montelukast in both children and adults, the clinician should discuss the possibility of these adverse events with the patient and parents,' said Meindina Haarman, lead author of the study.

Additional Information

Link to Study: http://doi.wiley.com/10.1002/prp2.341

About Journal

Pharmacology Research & Perspectives (PR&P) is a collaboration between the American Society for Pharmacology and Experimental Therapeutics (ASPET), the British Pharmacological Society (BPS) and Wiley. PR&P is an open access journal that publishes original research, reviews and perspectives in all areas of preclinical and clinical pharmacology, education and related research areas.

John Wiley & Sons Inc. published this content on 20 September 2017 and is solely responsible for the information contained herein.
Distributed by Public, unedited and unaltered, on 20 September 2017 04:14:05 UTC.

Original documenthttp://newsroom.wiley.com/press-release/pharmacology-research-perspectives/asthma-medication-may-have-psychiatric-side-effects

Public permalinkhttp://www.publicnow.com/view/8E3CC5A6ABB2F65E9BEA4B6982F688BEAA33CA73