Log in
E-mail
Password
Remember
Forgot password ?
Become a member for free
Sign up
Sign up
Settings
Settings
Dynamic quotes 
OFFON

4-Traders Homepage  >  Equities  >  London Stock Exchange  >  Puretech Health PLC    PRTC   GB00BY2Z0H74

SummaryQuotesChartsNewsAnalysisCalendarCompanyFinancialsConsensusRevisions 
News SummaryMost relevantAll newsSector newsTweets

PureTech Health : Announces Licensing Agreement between Commense and the University of British Columbia for Microbiome-Derived Therapy

share with twitter share with LinkedIn share with facebook
share via e-mail
0
05/11/2017 | 08:21pm CEST

By a News Reporter-Staff News Editor at Obesity & Diabetes Week -- PureTech Health plc ("PureTech Health" or the "Company", LSE:PRTC), an advanced, clinical-stage biopharmaceutical company, is pleased to announce a licensing agreement between Commense, Inc. ("Commense"), a subsidiary of PureTech Health, and the University of British Columbia ("UBC") for a microbiome-based therapy directed toward the prevention of asthma and other allergic diseases that present in childhood. This live biotherapeutic product bolsters Commense's pipeline of novel therapeutic programs designed to nurture a healthy microbiome early in life (see also PureTech Health).

The licensed technology was developed at UBC by B. Brett Finlay, Ph.D., Co-Founder and Scientific Advisory Board Member of the Company, Stuart Turvey, MBBS, D.Phil, FRCPC, and their colleagues and is based on their research published in Science Translational Medicine. Based on analysis of a longitudinal study, Dr. Finlay and his colleagues identified a transient imbalance early in life in children with atopy, wheeze, and asthma of four specific bacterial taxa: Faecalibacterium, Lachnospira, Veillonella, and Rothia (FLVR). In preclinical models of airway inflammation, signs of respiratory diseases, such as asthma, were ameliorated when live FLVR was introduced to correct the imbalance. The potential protective influence of FLVR in the early development of a child's immune system and against the development of asthma could have a significant impact on non-infectious, chronic diseases in children and adults.

"Asthma is a lifelong chronic disease that affects the quality of life of over 25 million Americans. The impact of using a defined microbial intervention to potentially change the natural course of asthma and prevent many cases of the disease could be profound," said Fernando Martinez, MD, Director of the Asthma and Airway Disease Research Center at the University of Arizona and a Clinical Advisor to Commense. "The FLVR supplementation approach uses defined gut-derived bacterial consortia against allergy and asthma. If this approach were to be successful, it would be a key step forward."

"Nurturing a healthy microbiome early in life represents a novel strategy to significantly reduce the impact of chronic diseases like asthma, allergies, diabetes, and obesity," said Joe Bolen, Ph.D., Chief Scientific Officer for PureTech Health. "Brett's work and contributions with FLVR build upon our arsenal of microbiome-derived therapeutics and may potentially impact childhood health in an important way."

Commense programs are part of PureTech Health's growing pipeline in immunology and microbiome-based therapeutics. These programs leverage the core expertise PureTech Health has developed through its Vedanta Biosciences subsidiary, allowing for accelerated development. Commense anticipates initiation of human clinical trials in 2019.

Keywords for this news article include: Asthma, Therapy, Pediatrics, Chronic Disease, PureTech Health, Disease Attributes, Risk and Prevention, Pathologic Processes, Respiratory Hypersensitivity, Bronchial Diseases and Conditions, Marketing and Licensing Agreements, Immune System Diseases and Conditions, Obstructive Lung Diseases and Conditions.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2017, NewsRx LLC

(c) 2017 NewsRx LLC, source Health Newsletters

share with twitter share with LinkedIn share with facebook
share via e-mail
0
Latest news on PURETECH HEALTH PLC
07/13 PURETECH HEALTH : Presents Data Supporting Treatment Approach for Interstitial C..
07/12 PURETECH HEALTH : Gelesis Announces Last Patient Visit in the Pivotal Gelesis100..
07/12 PURETECH HEALTH : Gelesis Announces Last Patient Out in the Pivotal Gelesis100 W..
06/28 PURETECH HEALTH : Akili Appoints Former Cubist CEO, Rob Perez, as Executive Chai..
06/28 PURETECH HEALTH : Former Cubist CEO, DreamWorks Interactive CEO, and Google Chie..
06/01 PURETECH HEALTH : to Present at Jefferies 2017 Global Healthcare Conference
05/30 PURETECH HEALTH : Vedanta Biosciences Granted U.S. Patent Broadly Covering Metho..
05/30 VEDANTA BIOSCIENCES : Granted U.S. Patent Broadly Covering Methods of Treatment ..
05/25 PURETECH HEALTH : Vedanta Biosciences Granted Three U.S. Patents Broadly Coverin..
05/25 PURETECH HEALTH : to Present at Jefferies 2017 Global Healthcare Conference
More news
Financials ($)
Sales 2017 1,85 M
EBIT 2017 -100 M
Net income 2017 -66,8 M
Debt 2017 4,43 M
Yield 2017 -
P/E ratio 2017 -
P/E ratio 2018
EV / Sales 2017 223x
EV / Sales 2018 207x
Capitalization 408 M
Chart PURETECH HEALTH PLC
Duration : Period :
Puretech Health PLC Technical Analysis Chart | PRTC | GB00BY2Z0H74 | 4-Traders
Technical analysis trends PURETECH HEALTH PLC
Short TermMid-TermLong Term
TrendsNeutralBullishBearish
Income Statement Evolution
Consensus
Sell
Buy
Mean consensus BUY
Number of Analysts 5
Average target price 3,13 $
Spread / Average Target 82%
Managers
NameTitle
Daphne Zohar Chief Executive Officer & Executive Director
Bharatt M. Chowrira President, Chief Business & Strategy Officer
Joichi Ito Non-Executive Chairman
Stephen Muniz Chief Operations Officer, Secretary & Director
Michael F. MacLean Chief Financial Officer & Executive Vice President
Sector and Competitors
1st jan.Capitalization (M$)
PURETECH HEALTH PLC11.98%408
INCYTE CORPORATION33.20%27 350
QUINTILES IMS HOLDINGS INC19.03%19 536
LONZA GROUP30.49%16 761
CELLTRION, INC.--.--%12 153
ALKERMES PLC4.34%8 884