On January 8, 2016, Tekla Life Sciences Investors paid a special cash distribution of $0.71 per share. It is currently estimated that this distribution is derived from long-term capital gains. The composition of this and subsequent distributions may vary from quarter to quarter because it may be materially impacted by future realized gains and losses on securities. The aggregate of the net unrealized appreciation of portfolio securities and net realized gains on sale of securities is $161,693,847 of which $177,021,885 represents net unrealized appreciation of portfolio securities.

The following table sets forth the estimated amounts of the current distribution, paid January 8, 2016, and the cumulative distributions paid this fiscal year-to-date from the following sources: net investment income, net realized short-term capital gains, net realized long-term capital gains, and return of capital or other capital source. All amounts are expressed per common share.

                               
         

Current
Distribution

        

Percentage
Breakdown of
Current Distribution

        

Total Cumulative
Distributions for the
Fiscal Year to Date1

        

Percentage Breakdown
of the Total Cumulative
Distributions for the
Fiscal Year to Date1

Net Investment Income

       

$0.0000

       

0%

       

$0.0000

       

0%

Net Realized ST Cap Gains         $0.0000         0%         $0.0000         0%
Net Realized LT Cap Gains         $0.7100         100%         $1.1800         100%

Return of Capital or Other Capital Source

        $0.0000         0%         $0.0000         0%
TOTAL (per common share):         $0.7100         100%         $1.1800         100%
 

The table below includes information relating to Fund’s performance based on its NAV for certain periods.

               

Average annual total return at NAV for the period from November 30, 2010 through November 30, 2015

                26.99%
Annualized current distribution rate expressed as a percentage of NAV as of November 30, 20153                 2.85%
Cumulative total return at NAV for the fiscal year, through November 30, 20152                 7.96%
Cumulative fiscal year-to-date distribution rate expressed as a percentage of NAV as of November 30, 20151                 4.74%
 

You should not draw any conclusions about the Fund’s investment performance from the amount of this distribution or from the terms of the Fund’s managed distribution plan.

The amounts and sources of distributions reported in this press release are only estimates and are not being provided for tax reporting purposes. The actual amounts and sources of the amounts for tax reporting purposes will depend upon the Fund’s investment experience during the remainder of its fiscal year and may be subject to changes based on tax regulations. The Fund will send you a Form 1099-DIV for the calendar year that will tell you how to report these distributions for federal income tax purposes.

Tekla Life Sciences Investors (NYSE: HQL) is a closed-end fund that invests in companies in the life sciences industry.

Tekla Capital Management LLC, the Fund’s investment adviser, is a Boston, MA based healthcare-focused investment manager with approximately $2.9 billion of assets under management as of September 30, 2015. Tekla also serves as investment adviser to Tekla Healthcare Investors (NYSE: HQH), Tekla Healthcare Opportunities Fund (NYSE: THQ) and Tekla World Healthcare Fund (NYSE: THW), closed-end funds that invest in companies in the healthcare industry.

For information please visit www.teklacap.com or call (617) 772-8500.

1 The Fund’s current fiscal year began on October 1, 2015.
2 Cumulative total return at NAV is the percentage change in the Fund’s NAV and includes all distributions and assumes the reinvestment of those distributions for the period of September 30, 2015 through November 30, 2015.
3 This distribution is a one time payment to satisfy annual tax distribution requirements and therefore has been annualized for one period.